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Journal of Dental Research
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Basic Biological Sciences

Atherosclerosis in the Tongue of the Rhesus Monkey

R.S. Mostofi

Zoller Dental Clinic, and Department of Pathology, University of Chicago, 950 East 59th Street, Chicago, Illinois 60637

R.A. Goepp

Zoller Dental Clinic, and Department of Pathology, University of Chicago, 950 East 59th Street, Chicago, Illinois 60637

Atherosclerotic vascular lesions in rhesus monkey tongues were studied, in both induction and regression periods. Vascular lesions were induced by peanut oil and a combination of coconut oil and butter fat, which caused the rapid elevation of serum lipids of all the animals. Atherosclerotic lesions were found in the tongues of all animals on an atherogenic diet. Larger arteries were found to be more susceptible to the disease.

During the regression period animals received either a low-fat, low-chalesterol diet with or without cholestyramine, or an atherogenic diet with cholestyramine. Regression of the disease was more significant in animals on a low-fat, low-cholesterol and cholestyramine diet. Lesions in larger arteries in the tongues appeared to respond to the treatment more rapidly.

REFERENCES

  • Dreizen, S.; Levy, B.M.; and Bernick, S.: Diet-induced Atherosclerosis in the Marmoset, Proc Soc Exp Biol Med 143:1218-1223, 1973.[CrossRef][Medline] [Order article via Infotrieve]
  • Dreizen, S.; Vogel, J.J.; and Levy, B.M.: The Effect of Experimentally-induced Atherosclerosis in the Oral Structures of the Rabbit, Arch Oral Biod 16:43-50, 1971.[CrossRef]
  • Dreizen, S.; Stone, R.E.; and Stahl, S.S.: The Effect of Experimentally-induced Generalized Medial Atherosclerosis in the Oral Vessels of Rats, Arch Oral Biol 8:187-189, 1963.[Medline] [Order article via Infotrieve]
  • Dreizen, S.; Levy, B.M.; Stern, M.H.; and Bernick, S.: Human Lingual Atherosclerosis, J Oral Biol 19:813-817, 1974.[CrossRef]
  • Gomori, G.: A Rapid One-step Trichrome Stain, Am J Clin Path 20:661-665, 1950.[Medline] [Order article via Infotrieve]
  • Vesselinovitch, D.; Wissler, R.W.; Schaffner, T.; and Borensztajen, J.: The Effect of Various Diets on Atherogenesis in Rhesus Monkeys, Atherosclerosis 35:189-207, 1980.[CrossRef][Medline] [Order article via Infotrieve]
  • Swahn, B.: A Micromethod for the Determination of Total Lipids in Serum, Scand J Clin Lab Invest 5(SupplIX):7-9, 1953.[Medline] [Order article via Infotrieve]
  • Rush, R.L.; Leon, L.; and Turrell, J.: Automated Simultaneous Cholesterol and Triglyceride Determination on the Autoanalyzer Instrument. In: Advances in Automated Analysis, Thurmon Assoc., Miami, Florida: Technicon, International Congress, 1971, p. 503.
  • Wissler, R.W. and Vesselinovitch, D.: Experimental Models of Human Atherosclerosis, Ann NY Acad Sci 149:907-922, 1968.[Medline] [Order article via Infotrieve]
  • Wissler, R.W. and Vesselinovitch, D.: Atherosclerosis in Nonhuman Primates, Adv Veter Sci Comp Med 21:351-420, 1977.
  • Wissler, R.W. and Vesselinovitch, D.: Animal Models of Regression. In: Atherosclerosis IV, Berlin: Springer-Verlag, 1977, pp. 377-385.
  • Wissler, R.S. and Vesselinovitch, D.: Difference Between Human and Animal Atherosclerosis. In: Atherosclerosis III, Berlin: Springer-Verlag, 1974, pp. 319-325.
  • Wissler, R.W.: The Arterial Medial Cell, Smooth Muscle, or Multifunctional Mesenchyme, J Atherosclerosis Res 8:201-213, 1968.[CrossRef]
  • Glagov, S.: Hemodynamic Factors in Localization of Atherosclerosis, Acta Cardiol Suppl. II:311-337, 1965.
  • Glagov, S. and Ozoa, A.K.: Significance of the Relatively Low Incidence of Atherosclerosis in the Pulmonary, Renal, and Mesenteric Arteries, Ann NY Acad Sci 149:940-955, 1968.
  • Bevans, M.; Davidson, J.D.; and Ken-Dall, F.E.: Regression of Lesion in Canine Atherosclerosis, Arch Path 51:288-292, 1951.
  • Daoud, A.S.; Jarmolych, L.; Augus-Tyn, J.; Fritz, K.; Singh, J.K.; and Lee, K.T.: Regression of Advanced Atherosclerosis in Swine, Arch Path Lab Med 100:372-379, 1976.[Medline] [Order article via Infotrieve]
  • Vesselinovitch, D.; Wissler, R.W.; Fisher-Dzoga, K.; Hughes, R.H.; and Dubien, L.: Regression of Atherosclerosis in Rabbits, Atherosclerosis 19:259-275, 1974.[CrossRef][Medline] [Order article via Infotrieve]
  • Vesselinovitch, D.; Wissler, R.W.; Hughes, R.H.; and Borensztajen, J.: Reversal of Advanced Atherosclerosis in Rhesus Monkeys, Atherosclerosis 23:155-176, 1976.[CrossRef]
  • Stary, H.C.: Cell Proliferation and Ultrastructural Changes in Regressing Atherosclerotic Lesions After Reduction of Serum Cholesterol. In: Atherosclerosis III, Berlin: Springer-Verlag, 1974, pp. 187-190.
  • Wissler, R.W. and Vesselinovitch, D.: Studies of Regression of Advanced Atherosclerosis in Experimental Animals and Man, Ann NY Acad Sci 275:363-378, 1976.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 60, No. 11, 1876-1885 (1981)
DOI: 10.1177/00220345810600110801
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This Article
Right arrow Abstract Freely available
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Right arrow Alert me when this article is cited
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What's this?