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Calcium and cGMP in Isolated Rat Parotid Acinar Cells

Departments of Pediatrics and Basic Dental Sciences, University of Florida, Colleges of Medicine and Dentistry, Gainesville, Florida 32610

R.L. Boyd

Departments of Pediatrics and Basic Dental Sciences, University of Florida, Colleges of Medicine and Dentistry, Gainesville, Florida 32610

D. Bouchlas

Departments of Pediatrics and Basic Dental Sciences, University of Florida, Colleges of Medicine and Dentistry, Gainesville, Florida 32610

W. Farnham

Departments of Pediatrics and Basic Dental Sciences, University of Florida, Colleges of Medicine and Dentistry, Gainesville, Florida 32610

The role of calcium ions in the activation of guanylate cyclase and in the propagation of the effects of cGMP during activation of the muscarinic cholinergic receptors was studied in isolated rat parotid acinar cells. It was demonstrated that the requirement for extracellular calcium is complete in the transduction of information from the muscarinic receptor to the guanylate cyclase, and partial in the steps beyond the synthesis of cGMP.

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Journal of Dental Research, Vol. 59, No. 8, 1442-1446 (1980)
DOI: 10.1177/00220345800590081401


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Mangos, J.A. Articles by Farnham, W. Search for Related Content PubMed PubMed Citation Articles by Mangos, J.A. Articles by Farnham, W. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB CALCIUM COMPOUNDS CALCIUM, ELEMENTAL POTASSIUM Social Bookmarking                         What's this?