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Basic Biological Sciences

DNA Synthesis of Enamel Organ Epithelium in vitro is Enhanced by Co-cultivation with Non-Viable Mesenchyme Cells

Laboratory for Developmental Biology, Department of Basic Sciences (Biochemistry Division), School of Dentistry, University of Southern California, Los Angeles, California 90007

Linda J. Rovero

Laboratory for Developmental Biology, Department of Basic Sciences (Biochemistry Division), School of Dentistry, University of Southern California, Los Angeles, California 90007

Developing enamel organ epithelium was cultured in the presence and absence of non-viable dental papilla mesenchyme cells. Epithelial cell proliferation was enhanced by 75% when cultivated on the mesenchyme cell substratum. The addition of epidermal growth factor (EGF) to enamel organ epithelium cultured on this substratum resulted in a synergistic enhancement of DNA synthesis.

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Journal of Dental Research, Vol. 59, No. 6, 1075-1080 (1980)
DOI: 10.1177/00220345800590061901


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Brownell, A. G. Articles by Rovero, L. J. Search for Related Content PubMed PubMed Citation Articles by Brownell, A. G. Articles by Rovero, L. J. Social Bookmarking                         What's this?