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Clinical Science Population Distribution of Human Salivary Amylases: Differential Inhibition by Wheat Protein

Department of Biological Sciences, Douglass College

Marian L. Rivas

Department of Biological Sciences, Douglass College

David H. Strumeyer

Department of Biochemistry and Microbiology, Cook College, and Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08903

Based upon response to an inhibitor from wheat gliadin, 80 random samples of human salivary amylase were separated into three phenotypic groups. Each phenotype occurred with a high frequency rendering this a polymorphic locus. The susceptibility to the inhibitor may be a useful marker for studies of tendency to caries and periodontal disease as well as for studies of genetic variation and linkage.

REFERENCES

• Vacikova, A.: Assessment of Electrophoretic Mobilities of Some Isoamylases, J Chromatog 69(2):349-354, 1972.[CrossRef][Medline] [Order article via Infotrieve]
• Ward, J.C.; Merritt, A.D.; and Bixler, D.: Human Salivary Amylase: Genetics of Electrophoretic Variants, Am J Hum Genet 23(4):403-409, 1971.[Medline] [Order article via Infotrieve]
• Skude, G.: Combined Electrophoretic and Immunological Methods in the Study of Human Amylases, Hereditas 65:277-284, 1970.[Medline] [Order article via Infotrieve]
• Boettcher, B. and De La Lande F.A.: Electrophoresis of Human Saliva and Identification of Inherited Variants of Amylase Isozymes, Aust J Exp Med Sci 47:97-103, 1969.[CrossRef]
• Kamaryt, J. and Laxova, R.: Amylase Heterogeneity Variants in Man, Humangenetik 3:41-45, 1966.[CrossRef][Medline] [Order article via Infotrieve]
• Merritt, A.D. and Karn, R.C.: In Advances in Human Genetics. Volume 7, Harry Harris and Kurt Hirschorn, Eds., New York: Plenum Press, 1977.
• Merritt, A.D.; Rivas, M.L.; Bixler, D.; and Newell, R.C.: Salivary and Pancreatic Amylase: Electrophoretic Characterizations and Genetic Studies, Am J Hum Genet 25(5):510-522, 1973a.[Medline] [Order article via Infotrieve]
• Clark, S.W.; Glaubiger, G.A.; and La Du B.N.,: Properties of Plasma Cholinesterase Variants, Ann N Y Acad Sci 151: 710-722, 1968.[Medline] [Order article via Infotrieve]
• Simpson, N.E. and Kalow, W.: The Silent Gene for Serum Cholinesterase, Am J Hum Genet 16:180-188, 1964.[Medline] [Order article via Infotrieve]
• Kalow, W. and Genest, K.: A Method for the Detection of Atypical Forms of Human Serum Cholinesterases. Determination of Dibucaine Numbers, Canad J Biochem Physiol 35:339-346, 1957.
• Strumeyer, D.H.: Protein Amylase Inhibitors in the Gliadin Fraction of Wheat and Rye Flour: Possible Factors in Celiac Disease, Nutr Rep Int 5(1):45-52, 1972.[Medline] [Order article via Infotrieve]
• Fisher, B.: Purification and Partial Characterization of an Alpha-amylase Inhibitor. Master's thesis, Rutgers University, New Brunswick, N. J., 1974.
• Bernfeld, P.: In Methods in Enzymology. S. P. Colowick and N. O. Kaplan, Eds., Volume 1, New York: Academic Press, 1955, pp. 149-158.
• Whittaker, M. and Barry, M.: The Pseudocholinesterase Variants: A Family Segregating for Two Homozygotes With the Fluoride Resistant Gene, Human Heredity 22:243-248, 1972.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 59, No. 6, 1010-1015 (1980)
DOI: 10.1177/00220345800590060101


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Rosenberg Gertzman, G. B. Articles by Strumeyer, D. H. Search for Related Content PubMed PubMed Citation Articles by Rosenberg Gertzman, G. B. Articles by Strumeyer, D. H. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Social Bookmarking                         What's this?