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Journal of Dental Research
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The Effect of Desalivation Upon Pulpal Function and Dental Caries in Rats

R.R. Steinman

Department of Oral Medicine, School of Dentistry, School of Medicine, Loma Linda University, Loma Linda, California 92350, Department of Physiology, School of Medicine, Loma Linda University, Loma Linda, California 92350

John Leonora

Department of Oral Medicine, School of Dentistry, School of Medicine, Loma Linda University, Loma Linda, California 92350, Department of Physiology, School of Medicine, Loma Linda University, Loma Linda, California 92350

Rashmi J. Singh

Department of Oral Medicine, School of Dentistry, School of Medicine, Loma Linda University, Loma Linda, California 92350, Department of Physiology, School of Medicine, Loma Linda University, Loma Linda, California 92350

The role of pulp and saliva in caries susceptibility and resistance was evaluated using a combination of endodontic treatment and desalivation. Evidence was presented that the pulp plays a major role in caries susceptibility. It is suggested that pulpal function is modified by hormonal factor(s) originating from salivary glands. In the rat, saliva appears to play a minor role in resistance to caries.

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Journal of Dental Research, Vol. 59, No. 2, 176-185 (1980)
DOI: 10.1177/00220345800590021801
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