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Some Observations on in vitro Dental Plaques
B.G. Bibby
Eastman Dental Center, 625 Elm wood Avenue, Rochester, New York 14620
C.T. Huang
Eastman Dental Center, 625 Elm wood Avenue, Rochester, New York 14620
A method is described for growing plaques in vitro in a flow of human saliva. Similarities between these in vitro plaques and natural in vivo plaques are seen in physical properties, bacterial composition, and pH response to sucrose solution.
REFERENCES
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- Pinto, F.R.: The Use of Saliva Substitutes in the Development of in vitro Plaque, New York: University of Rochester; 1976. Thesis.
- Huang, C.T.: Observations on in vitro Dental Plaque Formation, New York: University of Rochester; 1977. Thesis.
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- Bibby, B.G.: The Bacterial Flora in Different Parts of the Mouth, J Dent Res 17:471, 1938.[Free Full Text]
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- Bibby, B.G.; VanKesteren, M.; and Berry, G.P.: Studies on the Antibacterial Factors of Human Saliva, J Bact 43:573-583, 1942.[Free Full Text]
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- Theilade, E.; Wright, W.H.; Jensen, S.B.; and Loë, H.: Experimental Gingivitis in Man. A Longitudinal Clinical and Bacteriological Investigation, J Periodont Res 1:1, 1966.[CrossRef][Medline]
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- Stephan, R.M.: Intra-oral Hydrogen-ion Concentrations Associated with Dental Caries Activity, J Dent Res 23:256, 1944.
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- Edgar, W.M.; Bibby, B.G.; Mundorff, S.A.; and Rowley, J.: Acid Production in Plaque After Eating Snacks: Modifying Factors in Foods, JADA 90:418, 1975.
- Bibby, B.G.; Huang, C.T.; Zero, D.; Mundorff, S.A.; and Little, M.F.: Protective Effect of Milk Against in vitro Caries, J Dent Res (in press).
Journal of Dental Research, Vol. 59, No. 11,
1946-1952 (1980)
DOI: 10.1177/00220345800590110401

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