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Effect of Pulsed High Frequency Electromagnetic Radiation on Embryonic Mouse Palate in vitro
Richard J. Lieb
Departments of Anatomy and Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, Department of Pharmacology, Fairleigh Dickinson University, School of Dentistry, Hackensack, New Jersey 07601
William Regelson
Departments of Anatomy and Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, Department of Pharmacology, Fairleigh Dickinson University, School of Dentistry, Hackensack, New Jersey 07601
Brian West
Departments of Anatomy and Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, Department of Pharmacology, Fairleigh Dickinson University, School of Dentistry, Hackensack, New Jersey 07601
Robert L. Jordan
Departments of Anatomy and Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, Department of Pharmacology, Fairleigh Dickinson University, School of Dentistry, Hackensack, New Jersey 07601
Dominick P. DePaola
Departments of Anatomy and Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, Department of Pharmacology, Fairleigh Dickinson University, School of Dentistry, Hackensack, New Jersey 07601
Palatal shelves from 14-day-old embryonic mice were exposed to a 27.12 MHz pulsed non-ionizing radiofrequency (Diapulse) for 20 min followed by 24-hour organ culture in nutrient agar. Diapulse-treated palatal shelves showed induction of cartilage within the mesenchymal compartment and loss of the overlying epithelium in contrast to controls which were free of cartilage. The results are thought to be independent of thermal changes and may be due to calcium flux within the tissue.
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Journal of Dental Research, Vol. 59, No. 10,
1649-1652 (1980)
DOI: 10.1177/00220345800590101501

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