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Journal of Dental Research
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Cariogenicity of Mutants of Streptococcus mutans

Michael W.H. Mao

College of Dentistry, The Ohio State University, Columbus, Ohio 43210

Sam Rosen

College of Dentistry, The Ohio State University, Columbus, Ohio 43210

In this study, we induced a number of mutants of S. mutans differing in their abilities to synthesize glucan and produce acid. When tested for cariogenicity in gnotobiotic rats, "high pH" mutants caused less caries, but could not supplant a cariogenic parent strain.

REFERENCES

  • Gibbons, R.J. and Van Houte, J.: Dental Caries, Ann Rev Med 26:121-136, 1975.[CrossRef][Medline] [Order article via Infotrieve]
  • Fitzgerald, R.J.: Dental Caries Research in Gnotobiotic Animals, Caries Res 2:139-146,1968.[Medline] [Order article via Infotrieve]
  • Edwardsson, S.: Characteristics of Caries-inducing Human Streptococci Resembling Streptococcus mutans, Arch Oral Biol 13: 637-646, 1968.[CrossRef][Medline] [Order article via Infotrieve]
  • Perch, B.; Kjems, E.; and Ravn, T.: Biochemical and Serological Properties of Streptococcus mutans from Various Human and Animal Sources, Acta Path Microbiol 82(B):357-370, 1974.
  • Shklair, 1. and Keene, A.: A Biochemical Scheme for the Separation of the Five Varieties of Streptococcus mutans, Arch Oral Biol 19:1079-1081,1974.[CrossRef][Medline] [Order article via Infotrieve]
  • Bratthall, D.: Demonstration of Five Serological Groups of Streptococcal Strains Resembling Streptococcus mutans, Odontol Revy 21:143-152, 1970.[Medline] [Order article via Infotrieve]
  • Michalek, S.M.; Shiota, T.; Ikeda, T.; Navia, J.M.; and McGhee, R.: Virulence of Streptococcus mutans: Biochemical and Pathogenic Characteristics of Mutant Isolates, Proc Soc Exp Biol Med 150:498-502, 1975.[CrossRef][Medline] [Order article via Infotrieve]
  • Kuramitsu, H.K.: Properties of a Mutant of Streptococcus mutans Altered in Glucosyl-transferase Activity, Infect Immun 13:345-353, 1976.[Abstract/Free Full Text]
  • Niven, C.F.; Smiley, K.L.;and Sherman, J.M.: The Hydrolysis of Arginines by Streptococci, J Bacteriol 43:651, 1942.[Free Full Text]
  • McCabe, R.; Keyes, P.; and Howell, A., Jr.: An in vitro Method for Assessing the Plaque-forming Ability of Oral Bacteria, Arch Oral Biol 12:1653-1656, 1967.[CrossRef][Medline] [Order article via Infotrieve]
  • Rantz, L.A. and Randall, E.: Use of Autoclaved Extracts of Hemolytic Streptococci for Serological Grouping, Standford Med Bull 13:290-291, 1955.
  • Bright, J.S.; Rosen, S.; and Chorpenn-Ing, F.W.: Survey of the Seven Serological Types of Streptococcus mutans in Six-year-old Children, J Dent Res 56:1421, 1977.[Free Full Text]
  • Rosen, S.: A Simple and Accurate Method for Determining Mean pH, Arch Oral Biol 8:799, 1963.
  • Lamberts, B.L.;Meyer, T.S.;and Simon-Son L.G.: Investigation of Possible Solvents for Extracellular Polysaccharides from Streptococcus mutans and Streptococcus sanguis, J Dent Res 54:857-866, 1975.[Abstract/Free Full Text]
  • Dahlqvist, A.; Krasse, B.; Olsson, I.; and Gardell, S.: Extracellular Poly
  • saccharides Formed by Caries-inducing Streptococci, Helv Odont Acta 11:15-21, 1967.[Medline] [Order article via Infotrieve]
  • Dubois, M.: GILLES, K.A.; HAMILTON, J.K.; REBERS, P.A.; and SMITH, F.: Colorimetric Method for Determination of Sugars and Related Substances, Anal Chem 28:350, 1956.
  • Lowry, O.H.; Rosebrough, N.J.; Farr, A.L.; and Randall, R.J.: Protein Measurement with the Folin Phenol Reagent, J Biol Chem 193:265-275, 1951.[Free Full Text]
  • Keyes, P.H.: Dental Caries in the Molar Teeth of Rats. II. A Method for Diagnosing and Scoring Several Types of Lesions Simultaneously, J Dent Res 37:1077-1099, 1958.[Free Full Text]
  • Bratthall, D. and Kohler, B.: Streptococcus mutans Serotypes: Some Aspects of Their Identification, Distribution, Antigenic Shifts, and Relationship to Caries, J Dent Res 55(C):15-21, 1976.
  • Freedman, M.L. and Tanzer, J.M.: Dissociation of Plaque Formation from Glucan-induced Agglutination in Mutants of Streptococcus mutans, Infect Immun 10: 189-196,1974.[Abstract/Free Full Text]
  • Shinefield, H.R.; Ribble, J.C.; Boris, M.: Bacterial Interference Between Strains of Staphylococcus aureus, 1960-1979, Am J Diseases Children 121:148-152,1971.

Journal of Dental Research, Vol. 59, No. 10, 1620-1626 (1980)
DOI: 10.1177/00220345800590101101


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This Article
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PubMed
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Right arrow Articles by Rosen, S.
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What's this?