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Identification of Collagenase in Cultured Blood Mononuclear Cells

The University of Texas Dental Branch, Dental Science Institute, P.O. Box 20068, Houston, Texas 77025

B.F. Mackler

The University of Texas Dental Branch, Dental Science Institute, P.O. Box 20068, Houston, Texas 77025

Peggy O'Neill

The University of Texas Dental Branch, Dental Science Institute, P.O. Box 20068, Houston, Texas 77025

M.L. Mailman

The University of Texas Dental Branch, Dental Science Institute, P.O. Box 20068, Houston, Texas 77025

Mononuclear cells isolated from peripheral whole blood were fractionated by erythrocyte-rosetting into T cells and non-T cell subpopulations which were tested for collagenase-producing capacity. Mononuclear cells and purified T lymphocytes, as well as non-T (B) lymphocytes, produced collagenase during serum-free culture. Removal of the macrophages from the non-T cells did not affect collagenase production by lymphocytes.

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Journal of Dental Research, Vol. 59, No. 1, 2-10 (1980)
DOI: 10.1177/00220345800590010301


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Simpson, J. W. Articles by Mailman, M.L. Search for Related Content PubMed PubMed Citation Articles by Simpson, J. W. Articles by Mailman, M.L. Social Bookmarking                         What's this?