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Effects of Stannous Fluoride and Tiodonium Chloride on Dental Plaque in Rats
R.J. Shern
Caries Prevention and Research Branch, National Caries Program, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20205
K.M. Couet
Caries Prevention and Research Branch, National Caries Program, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20205
Rats with six-day-old plaque were treated twice daily with mouthrinses containing either tiodonium chloride, stannous fluoride or a placebo. Although the results for tiodonium chloride were unremarkable, stannous fluoride mouthrinses proved to be significantly effective in removing dental plaque and in restricting the ability of plaque to lower the pH of sugar solutions.
REFERENCES
- Stephan, R.M.: Intra-oral Hydrogen Ion Concentrations Associated With Dental Caries Activity. J Dent Res 23:256-266, 1944.
- Konig, K.G.: Dental Caries and Plaque Accumulation in Rats Treated With Stannous Fluoride and Penicillin. Helvet Odont Acta 3:39-44, 1959.
- Radike, A.W.; Gish, C.W.; Peterson, J.K.; King, J.D.; and Segreto, V.A.: Clinical Evaluation of Stannous Fluoride as an Anticaries Mouthrinse. JADA 86:404-408, 1973.
- Yankell, S.L.; Paskow, G.W.; and Shern, R.J.: Effects of SnF2 Mouthrinses on Plaque Microbiology. J Dent Res 57: A352, IADR Abstract 1109, 1978.
- Yankell, S.L.; Stoller, N.H.; Tawil, G.; Green, P.A.; and Shern, R.J.: Clinical Effects of Stannous Fluoride on Plaque Accumulation and Gingivitis. J Dent Res 57:A353, IADR Abstract 1113, 1978.
- Tinanoff, N.; Brady, J.M.; and Gross, A.: The Effect of NaF and SnF2 Mouthrinses on Bacterial Colonization of Tooth Enamel: TEM and SEM Studies. Caries Res 10:415-426, 1976.[Medline]
[Order article via Infotrieve]
- Sabourin, J.: Personal Communication, 1976.
- Yankell, S.L.; Stoller, N.H.; Tawil, G.; and Shern, R.J.: Clinical Effects of a DAPA-1 Mouthrinse on Plaque Accumulation and Gingivitis. J Dent Res 56:A47, IADR Abstract #19, 1977.
- Miller, C.J.; Shern, R.J.; and Mirth, D.B.: Plaque Restriction in the Rat Using a DAPA-1 Mouthrinse. J Dent Res 55:B287 Abstract #900, 1976.
- Schuster, G.S.: Personal Communication, 1976.
- Keyes, P.H., and Jordan, H.V.: Periodontal Lesions in the Syrian Hamster. III Findings Related to an Infectious Transmissible Component. Arch Oral Biol 9:377-400, 1964.[CrossRef]
- Jordan, H.V.; Fitzgerald, R.J.; and Bowler, A.E.: Inhibition of Experimental Caries by Sodium Bisulfite and Its Effect on Growth and Metabolism of Selected Bacteria. J Dent Res 39:116-123, 1960.[Free Full Text]
- Shannon, I.L.: Preventive Dental Services in the Veterans Administration Hospital. J Pub Health Dent 30:156-162, 1970.
- Glantz, P.O.: On Wettability and Adhesives. Odont Revy 20:Supplement 17,1969.
- Winer, B.J.: Statistical Principles of Experimental Design, New York: McGraw-Hill Book Co., 1962. p. 79.
- Stephan, R.M., and Miller, B.F.: The Effect of Synthetic Detergents on pH Changes in Dental Plaques. J Dent Res 22:53-61, 1943.[Free Full Text]
- Charlton, G.; Fitzgerald, D.B.; and Keyes, P.H.: Hydrogen Ion Activity in Dental Plaques of Hamsters during Metabolism of Sucrose, Glucose and Fructose. Arch Oral Biol 16:655-661, 1971.[CrossRef][Medline]
[Order article via Infotrieve]
- Shern, R.J.: Fluorescent and Infrared Intra-oral Color Photography. Abstract, p. 3. Ninth Joint Meeting of the Professional Associations of the U.S.P.H.S., April 1974.
- Lang, N.P.; Ostergaard, E.; and Löe, H.: A Fluorescent Plaque Disclosing Agent. J Perio Res 7:59-67, 1972.
- Lilienthal, B.: The Effect of a Stannous Fluoride Mouthwash on Acid Formation in the Mouth and Some Observations on the Mechanisms of Inhibition. Aust Dent J 1:221-227, 1956.
- Yankell, S.L.; Laster, L.L.; Green, P.A.; and Shern, R.J.: Effects of Stannous Fluoride on Saliva Glycolysis. J Dent Res 57:A337, IADR Abstract 1050, 1978.
- Miller, C.J.; Shern, R.J.; and Mirth, D.B.: Evaluation of the Antiplaque Potential of Tiodonium Chloride Utilizing a Rat Model. J Dent Res 55:B287, IADR Abstract 900, 1976.
- Rolla, G., and Melsen, B.: Desorption of Protein and Bacteria from Hydroxyapatite by Fluoride and Monofluorophosphate. Caries Res 9:66-73, 1975.[Medline]
[Order article via Infotrieve]
- Rolla, G.; Robrish, S.A.; and Bowen, W.H.: Interaction Between Hydroxyapatite and Protein-Coated Hydroxyapatite and Streptococcus mutans and Streptococcus sanguis. Acta Path Microbiol Scand Sect B, 85:341-346,1977.
- Doss, K.: Surface Properties of Hydroxyapatite: 1. The Effect of Various Inorganic Ions on Electrophoretic Behavior. J Dent Res 55:1067-1075.
- Mirth, D.B., and Miller, C.J.: Personal Communication, 1976.
- Bonesvoll, P., and Rolla, G.: Retention of SnF2 After Mouth Rinses. Caries Res 12:112,1978.
- Shern, R.J.; Couet, K.M.; and Weiss, L.: Unpublished data, 1977.
- Greene, J.C.: Oral Hygiene and Periodontal Disease. Amer J Public Health 53:913-922, 1962.
- Löe, H.; Theilade, E.; and Jensen, S.B.: Experimental Gingivitis in Man. J Periodont 36:177-187, 1965.
- Svatun, B.; Gjermo, P.; Eriksen, H.; and Rolla, G.: A Comparison of the Plaque Inhibiting Activity of Stannous Fluoride and Chlorhexidine. J Dent Res 56:A47, IADR Abstract 18, 1977.
Journal of Dental Research, Vol. 58, No. 8,
1830-1835 (1979)
DOI: 10.1177/00220345790580081401
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