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Sensitivity of Human Oral Tumor Cells to Human Adenovirus

Dental School and Department of Microbiology, University of Texas Health Science Center, San Antonio, Texas 78284

Wendell D. Winters

Dental School and Department of Microbiology, University of Texas Health Science Center, San Antonio, Texas 78284

Human cells in early passage cultures of benign oral tumors, normal oral tissues, normal lung tissues and, especially, in long-term established oral carcinoma cultures were highly susceptible to infection by human adenovirus types 5, 21, and 31. In contrast, replication of each adenovirus type was markedly limited in inoculated cells of newly-established oral squamous cell carcinoma cultures.

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Journal of Dental Research, Vol. 58, No. 8, 1815-1823 (1979)
DOI: 10.1177/00220345790580081201


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