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Journal of Dental Research
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In vitro Collagen Synthesis of Tooth Germs from Newborn Rats with Protein-Energy Malnutrition

Tetsuo Nakamoto

Oral Science Research Laboratories, Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

Henry M. Mallek

Oral Science Research Laboratories, Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

Sanford A. Miller

Oral Science Research Laboratories, Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

Mineralization and matrix formation are closely related processes in the growth and development of both incisor and molar tooth germs. Addition of ascorbic acid does not affect in vitro collagen synthesis of tooth germs from protein-energy malnourished rats.

REFERENCES

  • Nakamoto, T.; and Miller, S.A.: Effect of Protein-Energy Malnutrition on the Growth of Mandible and Long Bone in Newborn Male and'Female Rats, J Nutr 107:983-989, 1977.[Abstract/Free Full Text]
  • Russo;-A.R.; Sammons, D.; Nakamoto, T.; and Miller, S.A.: The Effects of Protein Malnutrition on the Growth of Salivary Glands in Newborn Male and Female Rats, Nutr Rep Int 17:93-100, 1978.
  • Shaw, J.H.: Pre-eruptive Effects of Nutrition on Teeth, J Dent Res 49:1238-1250, 1970.[Free Full Text]
  • Diorio, L.P.; Miller, S.A.; and Navia, J.M.: The Separate Effects of Protein and Calorie Malnutrition on the Development and Growth of Rat Bones and Teeth, J Nutr 103:856-865, 1973.[Abstract/Free Full Text]
  • Fabian, T.; Szelenyi, I.; Zelles, T.; and Fejerdy, P.: Influence of Dietary Protein Intake on the Incisors of Rats, Acta Med Acad Sci Hung 29:339-345, 1972.
  • Nakamoto, T.; Mallek, H.M.; and Miller, S.A.: The Effect of Protein-Energy Malnutrition on the Growth of Tooth Germs in Newborn Rats, J Dent Res, 58:1115-1122, 1979.[Abstract/Free Full Text]
  • Mallek, H.M.; Nakamoto, T.; Nuchtern, E.; and Miller, S.A.: The Effect of Calcitonin in Vitro on Tooth Germs in Protein-Energy Malnourished Rats, J Dent Res, in press.
  • Schiltz, J.R.; Rosenbloom, J.; and Levenson, G.E.: The Effects of Ascorbic Acid Deficiency on Collagen Synthesis by Mouse Molar Tooth Germ in Organ Culture, J Embryol Exp Morphol 37:49-57, 1977.[Medline] [Order article via Infotrieve]
  • Hazek, A.S.; and Solursh, M.: The Effect of Ascorbic Acid on Growth and Synthesis of Matrix Components by Cultured Chick Embryo Chondrocytes, J Exp Zool 200:377-388, 1977.[CrossRef][Medline] [Order article via Infotrieve]
  • Rojkind, M.; and Gonzales, E.: An Improved Method for Determining Specific Radioactivities of Proline-14C and Hydroxyproline-14C in Collagen and in Noncollagenous Proteins, Anal Biochem 57:1-7, 1974.[CrossRef][Medline] [Order article via Infotrieve]
  • Dixon, W.J.; and Massey, F.J.: Introduction to Statistical Analysis, New York: McGraw-Hill, 1969, pp. 109-129.
  • Miller, S.A.: Nutrition in the Neonatal Development of Protein Metabolism, Federation Proc 29:1497-1502, 1970.[Medline] [Order article via Infotrieve]
  • Stetten, M.R.: Some Aspects of the Metabolism of Hydroxyproline, Studied with the Aid of Isotopic Nitrogen, J Biol Chem 181:31-37,1949.[Free Full Text]
  • Firschein, H.E.: Collagen Turnover in Calcified Tissues, Arch Biochem Biophys 119: 119-123, 1967.[CrossRef][Medline] [Order article via Infotrieve]
  • Bollet, A.J.: Effect of Protein Depletion on Skin and Bone Collagen, Mt Sinai J Med NY 38:445-449, 1970.
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  • Peterkofsky, B.; and Udenfriend, S.: Enzymatic Hydroxylation of Protein in Microsomal Polypeptide Leading to Formation of Collagen, Proc Nat Acad Sci USA 53:335-342,1965.[Free Full Text]

Journal of Dental Research, Vol. 58, No. 7, 1717-1721 (1979)
DOI: 10.1177/00220345790580071301


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This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
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Right arrow Email this article to a friend
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Right arrow Similar articles in PubMed
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Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Nakamoto, T.
Right arrow Articles by Miller, S. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nakamoto, T.
Right arrow Articles by Miller, S. A.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?