This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Kraal, J.H. Articles by Akaho, E. Search for Related Content PubMed PubMed Citation Articles by Kraal, J.H. Articles by Akaho, E. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB HEXYLRESORCINOL SODIUM CHLORIDE Social Bookmarking                         What's this?

Exposure Time and the Effect of Hexylresorcinol. on Bacterial Aggregates

College of Dentistry and College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536

A.A. Hussain

College of Dentistry and College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536

S.B. Gregorio

College of Dentistry and College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536

E. Akaho

College of Dentistry and College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536

The bactericidal effect of hexylresorcinol was assessed using bacterial aggregates. Increased drug concentration resulted in decreased survival of bacteria when the aggregates were exposed to hexylresorcinol for at least eight hours. This indicates that this drug may be effective against dental plaque only when available for long periods of time.

REFERENCES

• Feirer, W.A. and Leonard, V.: Hexylresorcinol in Oral Antisepsis With Special Reference to Solution S.T. 37, Dental Cosmos 69:882-892,1927.
• Allen, W.A. and Wright, I.S.: The Bactericidal Properties of the Solution S.T. 37 (Liquor hexylresorcinolis, 1:1,000), Arch Surg 17:834-839, 1928.[Abstract/Free Full Text]
• Bunting, R.W.; Crowley, M.; Hard, D.G.; and Keller, M.: The Prevention of Dental Caries Through the Limitation of the Growth of Baccillus Acidophilus in the Mouth, JADA 4:224-230, 1929.
• Windholz, M. (Ed.): The Merck Index, 9th Ed., Rahway, New Jersey: Merck & Co., 1976.
• Bunting, R.W.; Hadley, F.P.; Jay, P.; and Hard, D.G.: The Problem of Dental Caries, Amer J Diseases Children 40:536-548,1930.
• Evans, R.T.; Baker, P.J.; Coburn, R.A.; Fischman, S.L.; and Genco, R.J.: In vitro Antiplaque Effects of Antiseptic Phenols, J Periodont 48:156-162, 1977.
• Jordan, H.V.; Fitzgerald, R.J.; and Bowler, A.E.: Inhibition of Experimental Caries by Sodium Metabisulfite and Its Effect on the Growth and Metabolism of Selected Bacteria, J Dent Res 39:116-123, 1960.[Free Full Text]
• Mccabe, R.M.; Keyes, P.M.; and Howell, A., Jr.: An In vitro Method for Assessing The Plaque Forming Ability of Oral Bacteria, Archs Oral Biol 12:1653-1656, 1967.
• Ratel, N.K. and Kostenbauder, H.B.: Interaction of Preservatives With Macro Molecules. I. Binding of Parahydroxybenzoic Acid Esters by Polyoxyethylene 20 Sorbitan Monooleate (Tween 80), J Amer Pharmaceut Assoc Scientific Ed, 47:289-292, 1958.
• Newbrun, E.: Polysaccharide Synthesis in Plaque, Proceedings "Microbial Aspects of Dental Caries." Eds. Stiles, Loesche and O'Brien, Sp Supp Microbiology Abstracts Vol 3:649-664,1976.

Journal of Dental Research, Vol. 58, No. 11, 2125-2131 (1979)
DOI: 10.1177/00220345790580111501


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Kraal, J.H. Articles by Akaho, E. Search for Related Content PubMed PubMed Citation Articles by Kraal, J.H. Articles by Akaho, E. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB HEXYLRESORCINOL SODIUM CHLORIDE Social Bookmarking                         What's this?