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Microbial Characterization of an Experimental Cariogenic Plaque in Man

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Theodore Koulourides

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Frances Hickman

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Jerry R. McGhee

Institute of Dental Research and Department of Oral Biology, School of Dentistry, University of Alabama in Birmingham, Birmingham, Alabama 35294, USA

Experimentally induced plaque seemed to originate by direct contact inoculation from the vestibular mucosa and saliva. During the next seven days, this plaque developed its own characteristics. Populations of Streptococcus mutans, usually less than 2% of total streptococci population in plaques that were less than three days old, increased between days 3 and 7. Proportions of S sanguis, high in early samples, decreased after day 3. Populations of S salivarius, which usually outnumbered other streptococci, fluctuated widely through day 3, and then increased in proportion in subjects who were more productive of experimental caries, but decreased in subjects who were less productive. Proportions of plaque flora comprising lactobacilli paralleled those of S salivarius.

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Journal of Dental Research, Vol. 56, No. 6, 550-558 (1977)
DOI: 10.1177/00220345770560060101


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