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Ceramic Hydroxylapatite as a Plaque Growth and Drug Screening Substrate

Sterling-Winthrop Research Institute, Division of Sterling Drug Inc., Rensselaer, New York 12144, USA

J.R. O'Connor

Sterling-Winthrop Research Institute, Division of Sterling Drug Inc., Rensselaer, New York 12144, USA

D.A. Paris

Sterling-Winthrop Research Institute, Division of Sterling Drug Inc., Rensselaer, New York 12144, USA

The preparation and use of a ceramic hydroxylapatite plaque growth and drug screening substrate is described. This material has been shown to closely mimic dental enamel in vitro in regard to the rate of plaque accumulation and the effectiveness of antiplaque drugs.

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Journal of Dental Research, Vol. 56, No. 2, 151-156 (1977)
DOI: 10.1177/00220345770560020901


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