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Degenerative Changes in Masseter Muscle Following Injection of Lidocaine : A Histoehemical Study

Departments of Oral and Maxillofacial Surgery, Restorative Dentistry and Anatomy, Virginia Commonwealth University, Richmond, Virginia 23298, USA

F.M. Bush

Departments of Oral and Maxillofacial Surgery, Restorative Dentistry and Anatomy, Virginia Commonwealth University, Richmond, Virginia 23298, USA

H.R. Seibel

Departments of Oral and Maxillofacial Surgery, Restorative Dentistry and Anatomy, Virginia Commonwealth University, Richmond, Virginia 23298, USA

G.W. Burke, JR.

Departments of Oral and Maxillofacial Surgery, Restorative Dentistry and Anatomy, Virginia Commonwealth University, Richmond, Virginia 23298, USA

Changes in suceinic dehydrogenase, adenosine triphosphatase, and phosphorylase activities occurred in masseter muscle by 15 minutes following injeetion of 2% lidocaine. Abolishment of phosphorylase activity suggested an effect on the sarcoplasmic retieulum. Increased staining for succinic dehydrogenase and adenosine triphosphatase activities suggested damage to mitochondria and myofibrils, respectively. Leucine aminopeptidase and glucose-6-phosphate dehydrogenase activities appeared in macrophages.

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Journal of Dental Research, Vol. 56, No. 11, 1395-1402 (1977)
DOI: 10.1177/00220345770560112001


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Dolwick, M.F. Articles by Burke, G.W. Search for Related Content PubMed PubMed Citation Articles by Dolwick, M.F. Articles by Burke, G.W., JR. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB LIDOCAINE Social Bookmarking                         What's this?