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Journal of Dental Research
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Effect of Topical Application of Fluoride on the Healing Rate of Experimental Calvarial Defects in Rats

T. Biller

Department of Preventive Dentistry, Faculty of Dentistry, The Hebrew University, Department of Orthopedics, Hadassah University Hospital, Jerusalem, Israel

Z. YosipoVitch

Department of Preventive Dentistry, Faculty of Dentistry, The Hebrew University, Department of Orthopedics, Hadassah University Hospital, Jerusalem, Israel

I. Gedalia

Department of Preventive Dentistry, Faculty of Dentistry, The Hebrew University, Department of Orthopedics, Hadassah University Hospital, Jerusalem, Israel

Bone gain was achieved after topical application of fluoride. Fluoride has a strong promoting effect on osteogenesis and accelerates the repair process of defects in membranous bone. No major histological differences are evident in the newly formed bone.

REFERENCES

  • Gedalia, I., and Zipkin, I.: The Role of Fluoride in Bone Structure, St. Louis: Warren H. Green, Inc., 1973, pp 17-22.
  • Jowsey, J., and Kelly, P.J.; Effect of Fluoride Treatment in a Patient with Osteoporosis, Mayo Clin Proc 43:435-443, 1968.[Medline] [Order article via Infotrieve]
  • Degubareff, N., and Platt, W.R.: Influence of Sodium Fluoride on Healing of Experimental Fractures, Arch Environ Health 19:22-31, 1969.[Medline] [Order article via Infotrieve]
  • Stein, E., and Buskin, S.A.: The Osteogenic Response After the Local Application of Fluoride to Bone, J Dent Res 48: 1157-1158, 1969.
  • Shambaugh, G.E., JR., and Petrovic, A.: Effects of Sodium Fluoride on Bone: Application to Otosclerosis and Other Decalcifying Bone Diseases, JAMA 204:969-973, 1968.[Abstract/Free Full Text]
  • Gedalia, I.; Azaz, B.; Garfunkel, A.: Different Methods of Topical Applications of Fluorides, Isr J Dent Med 21:130-132, 1972.[Medline] [Order article via Infotrieve]
  • Pritchard, J.: Repair of Fractures of the Parietal Bone in Rats, J Anat 30:55-60, 1976.
  • Burger, M.; Sherman, B.S.; and Sobel, A.E.: Observations of the Influence of Chondroitin Sulfate on the Rate of Bone Repair, J Bone Joint Surg (Br) 44B:675-687, 1962.
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  • Herold, H.Z.; Lupo, L.; Tadmor, A.; and Mirelman, D.: Stimulation of Osteoblastic Activity with Components of Cartilage Extract, Isr J Med Sci 10:1438-1447, 1974.[Medline] [Order article via Infotrieve]
  • Librus, H.; Pietrokovski, J.; Ulmanski, M.; and Gedalia, I.: The Effect of Fluoride on Molar Socket Healing in the Rat, Arch Oral Biol 18:1283-1289, 1973.[CrossRef][Medline] [Order article via Infotrieve]
  • Weis, H.Y., and Forbes, W.C.: Reactions of Powdered Sound Dentin with Several Fluoride Solutions, J Dent Res 48:149-152, 1969.[Abstract/Free Full Text]
  • Shulman, L.B.; Gedalia, I.; and Feingold, R.: Fluoride Concentration in Root Surfaces and Alveolar Bone of Fluoride-Immersed Monkey Incisors Three Weeks After Replantation, J Dent Res 52:1314-1316, 1973.[Abstract/Free Full Text]
  • Gedalia, I.; Singer, L.; Vogel, J.J.; and Armstrong, W.D.: Fetal and Neonatal Fluoride Uptake by Calcified Tissues of Rats, Isr J Med Sci 3: 726-730, 1967.
  • Rich, C., and Feist, E.: The Action of Fluoride on Bone, in Vischer, T.L. (ed): Fluoride in Medicine, Bern: Hans Huber, 1970, pp 70-87.

Journal of Dental Research, Vol. 56, No. 1, 53-56 (1977)
DOI: 10.1177/00220345770560011201
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This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Biller, T.
Right arrow Articles by Gedalia, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Biller, T.
Right arrow Articles by Gedalia, I.
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