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Studies on Hypoxia: XI. Long-Term Effects on the Epiphyseal Plate—A Histomeric and Radioautographic Study

Departments of Oral Biology and Anatomy, and Program in Biology in Aging, The University of Michigan, Ann Arbor, Michigan 48104, USA

C.S. Koo

Departments of Oral Biology and Anatomy, and Program in Biology in Aging, The University of Michigan, Ann Arbor, Michigan 48104, USA

M.K. Kim

Departments of Oral Biology and Anatomy, and Program in Biology in Aging, The University of Michigan, Ann Arbor, Michigan 48104, USA

Rats were exposed to hypoxia for one week. The mean thickness of epiphyseal plates from control rats was 430 micrometers (µm) which was reduced to 313 µm in hypoxic rats. Radioautographic incorporation of 3H-phenylalanine by connective tissue cells in hypoxic rats was reduced up to 38% in control rats.

REFERENCES

• Kim, J.H., and Han, S.S.: Studies on Hypoxia: V. Effects of Anoxia on Developing Connective Tissue Cells in Rats, Anat Rec 165:531-542, 1969.[Medline] [Order article via Infotrieve]
• Smith, D.M., and Han, S.S.: Studies on Hypoxia: II. Autoradiographic Quantitation of Proline-3H Incorporation by Connective Tissue Cells of the Neonatal Hamster, J Dent Res 47: 244-251, 1968.[Abstract/Free Full Text]
• Han, S.S.; Kim, J.H.; and Burdi, A.R.: Studies on Hypoxia: VII. Effect of Prenatal Anoxia on Leucine 3H Incorporation of Neonatal Rat Pancreas and Submandibular Gland, Proc Exp Biol Med 136: 191-195, 1971.[CrossRef][Medline] [Order article via Infotrieve]
• Kim, J.H., and Han, S.S.: Studies on Hypoxia: III. Effects on Leucine 3H Incorporation by Submandibular Gland Cells of Rat Neonates, Proc Soc Exp Biol Med 130: 470-473, 1968.
• Park, J.H.: Cytologic Effects of Anoxia on Submandibular Glands of Neonatal Mice, J Kore Dent Assn 10: 307-316, 1972.
• Morawa, A.P., and Han, S.S.: Studies on Hypoxia: VIII. Ultrastructural and Biochemical Effects of Prolonged Exposure on Rat Parotid Glands, Exp Mol Pathol 21: 266-287, 1974.
• Kim, Y.G., and Han, S.S.: Studies on Hypoxia: IX. Ultrastructural and Biochemical Effects of One-Week Exposure on Rat Pancreas, Am J Anat, in press, 1976.
• Kim, Y.G., and Han, S.S.: Studies on Hypoxia: X. Effects of Synthetic Polyribonucleotides on Pancreas from Hypoxic and Control Rats: An Electron Microscopic and Biochemical Study, Exp Mol Pathol 23: 43-58, 1975.[Medline] [Order article via Infotrieve]
• Bachra, B.N.: Calcification of Connective Tissue, Int Rev Connect Tiss Res 5:165-208, 1970.[Medline] [Order article via Infotrieve]
• Morawa, A.P.: An Ultrastructural and Biochemical Study of the Effects of Hypoxia upon Rat Parotid Glands, PhD thesis, University of Michigan, 1973.
• Guttman, A.B., and Yu, T.F.: Further Studies of Relation of Glycogenolysis and Calcification in Cartilage, in Reifenstein, E.C. (ed): Metabolic Interrelations, Vol 1, New York: Josiah Macy Jr. Foundation, 1949, pp 11-26.
• Guttman, A.B., and Yu, T.F.: A Concept of the Role of Enzymes in Endochondral Calcification, in Reifenstein, E.C. (ed): Metabolic Interrelations, Vol 2, New York: Josiah Macy Jr. Foundation, 1950, pp 167-190.
• Guttman, A.B., and Yu, T.F.: A Further Consideration of Effects of Beryllium Salts on In Vitro Calcification of Cartilage, in Reifenstein, E.C. (ed): Metabolic Interrelations, Vol 3, New York: Josiah Macy Jr. Foundation, 1951, pp 90-104.
• Talmage, R.V.: Morphological and Physiological Considerations in a New Concept of Calcium Transport in Bone, Am J Anat 129: 467-476, 1970.[CrossRef][Medline] [Order article via Infotrieve]
• Mathews, J.L., and Martin, J.H.: Mitochondrial Granules in Chondrocytes, Calcif Tissue Res 3: 184-193, 1969.[Medline] [Order article via Infotrieve]
• Lehninger, A.L.: Biochemistry: The Molecular Basis of Cell Structure and Function, New York: Worth Publishers, Inc., 1972.
• Radden, B.G., and Fullmer, H.M.: Morphological and Histochemical Studies of Bone Repair in the Rat, Arch Oral Biol 14: 1243-1252, 1969.[Medline] [Order article via Infotrieve]
• Morawa, A.P.; Kim, Y.G.; and Han, S.S.: Unpublished observations, 1975.

Journal of Dental Research, Vol. 55, No. 3, 367-371 (1976)
DOI: 10.1177/00220345760550031301


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				C.S. Koo, M.K. Kim, and S.S. Han Studies on Hypoxia: XII. Detrimental Effects of Synthetic Polyribonucleotides on Epiphyseal Plates of Rats Exposed to Hypoxia Journal of Dental Research, July 1, 1976; 55(4): 643 - 647. [Abstract] [PDF]

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Han, S.S. Articles by Kim, M.K. Search for Related Content PubMed PubMed Citation Articles by Han, S.S. Articles by Kim, M.K. Social Bookmarking                         What's this?