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Journal of Dental Research
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Role of Sucrose in Colonization of Streptococcus mutans in Conventional Sprague-Dawley Rats

J. Van Houte

Forsyth Dental Center, Boston, Massachusetts 02115, USA

V.N. Upeslacis

Forsyth Dental Center, Boston, Massachusetts 02115, USA

H.V. Jordan

Forsyth Dental Center, Boston, Massachusetts 02115, USA

Z. Skobe

Forsyth Dental Center, Boston, Massachusetts 02115, USA

D.B. Green

Forsyth Dental Center, Boston, Massachusetts 02115, USA

Dietary sucrose, ranging in concentration from 1 to 56%, facilitated greater colonization of Streptococcus mutans on teeth than other carbohydrates. Satisfactory colonization in the absence of sucrose was also achieved, but required higher cell inoculums and appeared to be independent of coprophagy. The intake of a nonsucrose diet did not lead to the elimination of S mutans from the teeth. Other data suggest that S mutans cells have a certain affinity for the teeth in the absence of sucrose that may be of ecological significance, and that bacterial affinity is of importance even for colonization in fissures.

REFERENCES

  • Krasse, B.: The Effect of the Diet on the Implantation of Caries-Inducing Streptococci in Hamsters, Arch Oral Biol 10: 215-221, 1965.[CrossRef][Medline] [Order article via Infotrieve]
  • Krasse, B.: The Effect of Caries-Inducing Streptococci in Hamsters Fed Diets with Sucrose or Glucose, Arch Oral Biol 10: 223-226, 1965.[CrossRef][Medline] [Order article via Infotrieve]
  • Guggenheim, B.; König, K.G.; Herzog, E.; and Mühlmann, H.R.: The Cariogenicity of Different Dietary Carbohydrates Tested in Rats in Relative Gnotobiosis with a Streptococcus Producing Extracellular Polysaccharide, Helv Odontol Acta 10: 101-112, 1966.[Medline] [Order article via Infotrieve]
  • Edwardsson, S., and Krasse, B.: Human Streptococci and Caries in Hamsters Fed Diets with Sucrose or Glucose, Arch Oral Biol 12: 1015-1016, 1967.[CrossRef][Medline] [Order article via Infotrieve]
  • Krasse, B.; Edwardsson, S.; Svensson, I.; and Trell, L.: Implantation of Caries-Inducing Streptococci in the Human Oral Cavity, Arch Oral Biol 12: 231-236, 1967.[CrossRef][Medline] [Order article via Infotrieve]
  • DE Stoppelaar, J.D.; Van Houte, J.; and Backer Dirks, O.: The Effect of Carbohydrate Restriction on the Presence of Streptococcus mutans, Streptococcus sanguis and Iodophilic Polysaccharide-Producing Bacteria in Human Dental Plaque, Caries Res 4: 114-123, 1970.[Medline] [Order article via Infotrieve]
  • Cornick, D.E.R., and Bowen, W.H.: The Effect of Sorbitol on the Microbiology of the Dental Plaque in Monkeys (Macaca irus), Arch Oral Biol 17: 1637-1648, 1972.[CrossRef][Medline] [Order article via Infotrieve]
  • Huwley, H.G.: The Effect of the Dietary Carbohydrate upon the Colonization of Plaque by Streptococcus mutans in Rats, Arch Oral Biol 19:941-946, 1974.[CrossRef][Medline] [Order article via Infotrieve]
  • Rosen, S.: Comparison of Sucrose and Glucose in the Causation of Dental Caries in Gnotobiotic Rats, Arch Oral Biol 14: 445-450, 1969.[CrossRef][Medline] [Order article via Infotrieve]
  • Van Der Hoeven, J.S.: Glucose en Caries Preventie, Ned Tandartsen Blad 28: 359-361, 1973.
  • Edwardsson, S.; Koch, G.; and Öbrink, M.: Streptococcus sanguis, Streptococcus mutans and Streptococcus salivarius in Saliva. Prevalence and Relation to Caries Increment and Prophylactic Measures, Odontol Revy 23: 279-296, 1972.[Medline] [Order article via Infotrieve]
  • Van Houte, J., and Green, D.B.: Relationship Between the Concentration of Bacteria in Saliva and the Colonization of Teeth in Humans, Infect Immun 9: 624-630, 1974.[Abstract/Free Full Text]
  • Fitzgerald, R.J.; Keyes, P.H.; Stoudt, T.; and Spinell, D.M.: The Effects of a Dextranase Preparation on Plaque and Caries in Hamsters: a Preliminary Report, JADA 76: 301-304, 1968.
  • Taubman, M.A., and Smith, D.J.: Effects of Local Immunization with Streptococcus mutans on Induction of Salivary Immunoglobulin A Antibody and Experimental Dental Caries in Rats, Infect Immun 9: 1079-1091, 1974.[Abstract/Free Full Text]
  • Spinell, D.M., and Gibbons, R.J.: Influence of Culture Medium on the Glucosyltransferase and Dextran-Binding Capacity of Streptococcus mutans 6715 Cells, Infect Immun 10: 1448-1451, 1974.[Abstract/Free Full Text]
  • Van Houte, J.; Gibbons, R.J.; and Banghart, S.B.: Adherence as a Determinant of the Presence of Streptococcus salivarius and Streptococcus sanguis on the Human Tooth Surface, Arch Oral Biol 15: 1025-1034, 1970.[CrossRef][Medline] [Order article via Infotrieve]
  • Gibbons, R.J., and Fitzgerald, R.J.: Dextran-Induced Agglutination of Streptococcus mutans, and Its Potential Role in the Formation of Microbial Dental Plaques, J Bacteriol 98: 341-346, 1969.[Abstract/Free Full Text]
  • König, K.G., and Marthaler, T.M.: Eine Longitudinale Molarendurchbruchsstudie an Sprague-Dawley-Ratten, Helv Odontol Acta 4: 43-48, 1960.[Medline] [Order article via Infotrieve]
  • Barnes, R.H.; Fiala, G.; McGehee, B.; and Brown, A.: Prevention of Coprophagy in the Rat, J Nutr 63: 489-498, 1957.[Abstract/Free Full Text]
  • Gibbons, R.J.; Berman, K.S.; Knoettner, P.; and Kapsimalis, B.: Dental Caries and Alveolar Bone Loss in Gnotobiotic Rats Infected with Capsule-Forming Streptococci of Human Origin, Arch Oral Biol 11: 549-560. 1966.[CrossRef][Medline] [Order article via Infotrieve]
  • Frostell, G.; Keyes, P.H.; and Larson, R.H.: Effects of Various Sugars and Sugar Substitutes on Dental Caries in Hamsters and Rats, J Nutr 93: 65-76, 1967.[Abstract/Free Full Text]
  • Barnes, R.H.; Fiala, G.; and Kwong, E.: Decreased Growth Rate Resulting from Prevention of Coprophagy, Fed Proc 22: 125-128, 1963.[Medline] [Order article via Infotrieve]
  • Fitzgerald, R.J.; Gustafsson, B.E.; and McDaniel, E.G.: Effects of Coprophagy Prevention on Intestinal Microflora in Rats, J Nutr 84: 155-160, 1964.[Abstract/Free Full Text]
  • Tanzer, J.M.; Hageage, G.J.; and Larson, R.H.: Variable Experiences in Immunization of Rats against Streptococcus mutans-Associated Dental Caries, Arch Oral Biol 18: 1425-1439, 1973.[CrossRef][Medline] [Order article via Infotrieve]
  • De Stoppelaar, J.D.; König, K.G.; Plass-Chaert, A.J.M.; and Van Der Hoeven, J.S.: Decreased Cariogenicity of a Mutant of Streptococcus mutans, Arch Oral Biol 16: 971-975, 1971.[CrossRef][Medline] [Order article via Infotrieve]
  • Tanzer, J.M.; Freedman, M.L.; Fitzgerald, R.J.; and Larson, R.H.: Diminished Virulence of Glucan Synthesis-Defective Mutants of Streptococcus mutans, Infect Immun 10: 197-203, 1974.[Abstract/Free Full Text]
  • Shklair, I.L., and Keene, H.J.: Relationship of Streptococcus mutans in Plaque and Feces to Dental Caries, J Dent Res 52 (Special Issue): Abstract No. 594, 1973.
  • Van Houte, J., and Duchin, S.: Streptococcus mutans in the Mouths of Children with Congenital Sucrase Deficiency, Arch Oral Biol, in press.
  • Shklair, I.L.; Keene, H.J.; and Cullen, P.: The Distribution of Streptococcus mutans on the Teeth of Caries-Free and Caries-Active Naval Recruits, abstracted, IADR Program and Abstracts of Papers, No. 71, 1972.
  • Gibbons, R.J.; DE Paola, P.F.; Spinell, D.M.; and Skobe, Z.: Interdental Localization of Streptococcus mutans as Related to Dental Caries Experience, Infect Immun 9: 481-488, 1974.[Abstract/Free Full Text]
  • Gibbons, R.J., and Van Houte, J.: On the Formation of Dental Plaques, J Periodontol 44: 347-360, 1973.[Medline] [Order article via Infotrieve]
  • Van Houte, J., and Upeslacis, V.N.: Studies of the Mechanism of Sucrose-Associated Colonization of Streptococcus mutans on Teeth of Conventional Rats, J Dent Res 55: 216-222, 1976.[Abstract/Free Full Text]
  • Clark, W., and Gibbons, R.J.: Studies of the Attachment of Streptococcus mutans to Apatite Surfaces, J Dent Res 53 (Special Issue): Abstract No. 749, 1974.
  • Gustafson, G.: The Histopathology of Caries of Human Dental Enamel, with Special Reference to the Division of the Carious Lesion into Zones, Acta Odontol Scand 15: 13-55, 1957.[CrossRef]
  • König, K.G.: Dental Morphology in Relation to Caries Resistance with Special Reference to Fissures as Susceptible Areas, J Dent Res 42: 461-476, 1963.[Free Full Text]

Journal of Dental Research, Vol. 55, No. 2, 202-215 (1976)
DOI: 10.1177/00220345760550020801
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This Article
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