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Collagenolytic Activity of Crevicular Fluid from Pericoronal Gingival Flaps
Lorne M. Golub
School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, New York 11790, USA, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada
Stanley Kennett
School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, New York 11790, USA, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada
Helen Mcewan
School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, New York 11790, USA, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada
John B. Curran
School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, New York 11790, USA, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada
N.S. Ramamurthy
School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, New York 11790, USA, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada
Collagenolytic activity was seen in fluids from the mandibular pericoronal gingival flap. Based on the response of this activity to sodium thiocyanate, and on the disc gel electrophoretic pattern of the collagen breakdown products, the collagenase appeared to be of tissue rather than of bacterial origin. Moreover, this activity seemed to parallel the collagenase activity and the breakdown of collagen in the adjacent gingival tissue, and thus, may be of diagnostic importance.
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Journal of Dental Research, Vol. 55, No. 2,
177-181 (1976)
DOI: 10.1177/00220345760550020301
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