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Journal of Dental Research
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Adsorption of Salivary Proteins by Hydroxyapatite: Effects of Phosphate Ions and Interdependence of the Effects of Phosphate and Hydrogen Ions

Charles Mc Gaughey

Oral Diseases Research Laboratory, Veterans Administration Hospital, Long Beach, California 90801, USA

Ellery C. Stowell

Department of Biochemistry, School of Medicine, University of Southern California, Los Angeles, California

Phosphate ions at physiological concentrations in saliva inhibited adsorption of salivary proteins by hydroxyapatite. Adsorption was related inversely to the concentration of phosphate. Removal of phosphate from saliva abolished or decidedly lowered the stimulating effect of hydrogen ions on adsorption of salivary proteins. Lowering the pH decreased, abolished, or reversed the adsorption inhibitory effect of phosphate.

REFERENCES

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  • McGaughey, C., and Stowell, E.C.: The Adsorption of Salivary Proteins by Hydroxyapatite: Relations between the Effects of Calcium Ions, Hydrogen Ions, Temperature, and Exposure Time, J Dent Res 50: 542-550, 1971.
  • McGaughey, C., and Stowell, E.C.: A Specific Effect of Hydrogen Ions on the Adsorption of Salivary Proteins by Hydroxyapatite, Caries Res 5: 373-377, 1971.[Medline] [Order article via Infotrieve]
  • Rolla, G., and Mathiesen, P.: The Adsorption of Salivary Proteins and Dextrans to Hydroxyapatite, in McHugh, W.D. (ed): Dental Plaque, London: E. S. Livingstone, 1970.
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  • Beveridge, J.M.R., and Johnson, S.E.: The Determination of Phospholipid Phosphorous, Can J Res E 27: 159-163, 1949.
  • Ericson, T.: Salivary Glycoproteins. Composition and Adsorption to Hydroxyapatite in Relation to the Formation of Dental Pellicles and Calculus, Acta Odontol Scand 26: 3-21, 1968.[CrossRef][Medline] [Order article via Infotrieve]
  • Meckel, A.H.: The Formation and Properties of Organic Films on Teeth, Arch Oral Biol 10: 585-597, 1965.[CrossRef][Medline] [Order article via Infotrieve]
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  • Pruitt, K.M.; Caldwell, R.C.; Jamieson, A.D.; and Taylor, R.E.: The Interaction of Salivary Proteins with Tooth Surface, J Dent Res 48: 818-823, 1969.[Abstract/Free Full Text]

Journal of Dental Research, Vol. 53, No. 1, 121-126 (1974)
DOI: 10.1177/00220345740530010401


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This Article
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