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Mast Cells and Basophils in the Mandibular Alveolar Connective Tissue and Bone Marrow of Germfree Albino Rats

College of Dentistry, The Ohio State University, Columbus, Ohio 43210, USA

George R. App

College of Dentistry, The Ohio State University, Columbus, Ohio 43210, USA

Rudy C. Melfi

College of Dentistry, The Ohio State University, Columbus, Ohio 43210, USA

Mast cells and basophils decreased in numbers in older germfree rats. Degranulation of mast cells increased in older animals. It is possible that aging is related to increasing degranulation and the release of pharmacologically active substances such as heparin. The release of heparin might play a role in bone loss.

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Journal of Dental Research, Vol. 52, No. 5, 1092-1096 (1973)
DOI: 10.1177/00220345730520051801


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Wolf, J. E. Articles by Melfi, R. C. Search for Related Content PubMed PubMed Citation Articles by Wolf, J. E. Articles by Melfi, R. C. Social Bookmarking                         What's this?