|
Sign In to gain access to subscriptions and/or personal tools.
|
Effect of Undernutrition During the Perinatal Period on Caries Development in the Rat: III. Effects of Undernutrition on Biochemical Parameters in the Developing Submandibular Salivary Gland
Lewis Menaker
Institute of Dental Research, School of Dentistry, University of Alabama in Birmingham Medical Center, Birmingham, Alabama 35294, USA
Juan M. Navia
Institute of Dental Research, School of Dentistry, University of Alabama in Birmingham Medical Center, Birmingham, Alabama 35294, USA
Undernutrition imposed on rats during the suckling period led to diminished levels of the biologic compounds associated with protein biosynthetic pathways in the submandibular salivary gland. DNA, RNA, protein concentration, and total wet weight in undernourished rats did not return to control amounts after intubation with a supplement containing no protein. However, supplements of a solution containing 10% protein during early development completely restored control amounts.
REFERENCES
- Lowbeer, B.V.A.: Radiation Therapy and Dental Medicine, Oral Surg 4: 739-761, 1951.
- Schwartz, A., and Weisberger, D.: Salivary Factors in Experimental Animal Caries, in Sognnaes, R.F.: Advances in Experimental Caries Research, Washington, DC.: AAAS, 1955.
- Klapper, C.E., and Volker, J.F.: The Influence of Impaired Salivary Function on Dental Caries in the Syrian Hamster, J Dent Res 32: 219-223, 1953.[Free Full Text]
- Kouloupides, T.: Experimental Changes of Enamel Mineral Density, in Harris, R.S. (ed): The Art and Science of Dental Caries Research, New York: Academic Press, 1968.
- South, M.A.; Cooper, M.D.; Wollheim, F.A.; Hang, R.; and Good, R.A.: The IgA System. I. Studies of the Transport and Immunochemistry of IgA in the Saliva, J Exp Med 123: 615-627, 1966.[Abstract/Free Full Text]
- Brandtzaeg, P.: Human Secretory Immunoglobulins. VII. Concentrations of Parotid IgA and Other Secretory Proteins in Relation to the Rate of Flow and Duration of Secretory Stimulus, Arch Oral Biol 16: 1295-1310, 1971.[CrossRef][Medline]
[Order article via Infotrieve]
- Coleman, S.E.; Van Derijn, V.; and Blei-Weis, A.J.: Lysis of Cariogenic and Non-cariogenic Oral Streptococci with Lysozyme, j Dent Res 50: 934-943, 1971.[Abstract/Free Full Text]
- Menaker, L., and Navia, J.M.: The Effect of Undernutrition During the Perinatal Period on Caries Development in the Rat. II. Caries Susceptibility in Underfed Rats Supplemented with Protein or Calories During the Suckling Period, J Dent Res 52: 680-687, 1973.[Abstract/Free Full Text]
- Lowry, O.H.; Rosebrough, N.J.; Farr, A.L.; and Randall, R.J.: Protein Measurement with the Folin Phenol Reagent, J Biol Chem 193: 265-275, 1951.[Free Full Text]
- Wannemacher, R.W., JR.; Bank, W.L., JR.; and Wunner, W.H.: Use of a Single Tissue Extract to Determine Cellular Protein and Nucleic Acid Concentrations and Rate of Amino Acid Incorporation, Anal Biochem 11: 320-326,1965.[CrossRef][Medline]
[Order article via Infotrieve]
- Duncan, D.B.: Multiple Range and Multiple F Tests, Biometrics 11: 1-42, 1955.[Medline]
[Order article via Infotrieve]
- Enesco, M., and Leblond, C.P.: Increase in Cell Number as a Factor in Growth of the Organs and Tissues of the Young Male Rat, J Embryol Exp Morphol 10: 530, 1962.
- Winick, M., and Noble, A.: Cellular Response in Rats During Malnutrition at Various Ages, J Nutr 89: 300-306, 1966.[Abstract/Free Full Text]
- Miller, S.A., and Dymsza, H.A.: Artificial Feeding of Neonatal Rats, Science 141: 517-518, 1963.[Abstract/Free Full Text]
Journal of Dental Research, Vol. 52, No. 4,
688-691 (1973)
DOI: 10.1177/00220345730520040801
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
This article has been cited by other articles:
|
|
|
|
 
D.A. Johnson, H. Lopez, and J.M. Navia
Effects of Protein Deficiency and Diet Consistency on the Parotid Gland and Parotid Saliva of Rats
Journal of Dental Research,
August 1, 1995;
74(8):
1444 - 1452.
[Abstract]
[PDF]
|
|
|
|
|
|
|
I. Johansson, M. Lenander-Lumikari, and A.-K. Saellstrom
Saliva Composition in Indian Children with Chronic Protein-Energy Malnutrition
Journal of Dental Research,
January 1, 1994;
73(1):
11 - 19.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J.O. Alvarez, J. Caceda, T.W. Woolley, K.W. Carley, N. Baiocchi, L. Caravedo, and J.M. Navia
A Longitudinal Study of Dental Caries in the Primary Teeth of Children who Suffered from Infant Malnutrition
Journal of Dental Research,
December 1, 1993;
72(12):
1573 - 1576.
[Abstract]
[PDF]
|
|
|
|
|
|
|
I. Johansson, T. Ericson, W. Bowen, and M. Cole
The Effect of Malnutrition on Caries Development and Saliva Composition in the Rat
Journal of Dental Research,
January 1, 1985;
64(1):
37 - 43.
[Abstract]
[PDF]
|
|
|
|
|
|
|
L. Menaker and J. M. Navia
Effect of Undernutrition During the Perinatal Period on Caries Development in the Rat: IV. Effects of Differential Tooth Eruption and Exposure to a Cariogenic Diet on Subsequent Dental Caries Incidence
Journal of Dental Research,
July 1, 1973;
52(4):
692 - 697.
[Abstract]
[PDF]
|
|
|
|
|
