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Journal of Dental Research
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Effect of Undernutrition During the Perinatal Period on Caries Development in the Rat: II. Caries Susceptibility in Underfed Rats Supplemented with Protein or Caloric Additions During the Suckling Period

Lewis Menaker

Institute of Dental Research, School of Dentistry, University of Alabama in Birmingham Medical Center, Birmingham, Alabama 35233, USA

Juan M. Navia

Institute of Dental Research, School of Dentistry, University of Alabama in Birmingham Medical Center, Birmingham, Alabama 35233, USA

The specific role of protein deficiency in altering dental caries incidence in rat pups was investigated. A 10% protein supplement given to undernourished rats during development allowed them to overcome weight deficiencies and reversed dental caries to the low incidence found in well-nourished control rats. Caries in undernourished rats supplemented with an isocaloric, proteinfree solution, was as high as that of undernourished rats intubated with distilled water.

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Journal of Dental Research, Vol. 52, No. 4, 680-687 (1973)
DOI: 10.1177/00220345730520040701


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This Article
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