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Desorption of Salivary Proteins from Hydroxyapatite by Phytic Acid and Glycerophosphate and the Plaque-Inhibiting Effect of the Two Compounds In Vivo

Department of Physiology and Biochemistry, Department of Operative Dentistry, Dental Faculty, University of Oslo, Oslo, Norway

Gunnar Rölla

Department of Physiology and Biochemistry, Department of Operative Dentistry, Dental Faculty, University of Oslo, Oslo, Norway

The capacity of phytic acid and glycerophosphate to desorb salivary proteins from hydroxyapatite was studied in vitro. Phytic acid had a high capacity for desorption; the capacity of glycerophosphate was considerably lower. In vivo experiments showed that both substances were capable of reducing plaque formation; phytic acid had a greater effect. The results may offer an explanation of the cariostatic effect of these substances.

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Journal of Dental Research, Vol. 51, No. 3, 800-802 (1972)
DOI: 10.1177/00220345720510031701


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