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Autoradiographic Demonstration of DNA Synthesis in Selected Epithelial Tissues in Male Rats

School of Dentistry, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219

George W. Burke, JR

School of Dentistry, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219

Eleven white male rats received intravenous injections of thymidine -³H at a dose rate of 1 µc/gm body weight. The rats were killed at four-hour intervals over a 24-hour period Epithelial specimens from the hard and soft palate, cheek, skin, and tail were subjected to autoradiography. The results confirm prior data from liquid scintillation studies, which showed a maximal DNA synthesis at 4:30 to 8:45 AM and minimal synthesis at 3:40 to 8:30 PM.

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Journal of Dental Research, Vol. 48, No. 6, 1219-1223 (1969)
DOI: 10.1177/00220345690480062201


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by England, M. C. Articles by Burke, G. W. Search for Related Content PubMed PubMed Citation Articles by England, M. C., JR Articles by Burke, G. W., JR Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB TRITIUM Social Bookmarking                         What's this?