This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Lurie, A. Search for Related Content PubMed PubMed Citation Articles by Lurie, A. Social Bookmarking                         What's this?

Effects of Low Level X Radiation on the Mitotic Index of Hamster Basal Epithelial Cells In Vivo

Department of Dentistry and Dental Research, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14620

Chinese hamster cheek pouches were exposed to low doses of X radiation and to two doses of a metaphase arrester, vinblastine sulfate, in separate experiments. There was no significant decrease in the mitotic indexes of the irradiated animals. The higher vinblastine dose proved to be significantly more effective in causing metaphase arrest.

REFERENCES

• Gibbs, S.J.: Cytokinetic Effect of 'H and X Rays in Hamster Basal Epithelial Cells In Vivo PhD Thesis, University of Rochester, School of Medicine and Dentistry, 1968.
• Seydel, H.G., Mitotic Delay After Fractionated Irradiation of Autotransplants of a Spontaneous Mouse Tumor, Amer J Roentgen 100:938-942, 1967.[Medline] [Order article via Infotrieve]
• Sobkowski, F.J.: Studies of Chromosome Damage and Mitotic Response In Vivo in X Irradiated Mammalian Epithelium, PhD Thesis, University of Rochester, School of Medicine and Dentistry, 1965.
• Puck, T.T., and Marcus, P.I.: Life Cycle Analysis of Mammalian Cells I. A Method for Localizing Metabolic Events Within the Life Cycle, and Its Application to the Action of Colcemid and Sublethal Doses of X Irradiation, Biophys J 3:379-397, 1963.[Medline] [Order article via Infotrieve]
• Rubin, P., and Casarett, G.W.: Clinical Radiation Pathology, Vol I, Philadelphia: W.B. Saunders Co., 1968, pp 10-35.
• Whitmore, G.F.; Till, J.F.; and Gulyas, S. Radiation Induced Mitotic Decay in L Cells, Radiat Res 30:155-171, 1967.[CrossRef][Medline] [Order article via Infotrieve]
• Yamada, M.A., and Puck, T.T.: Action of Radiation on Mammalian Cells, IV. Reversible Mitotic Lag in the S3 Hela Cell Produced by Low Doses of X Rays, Proc Nat Acad Sci USA 47:1181-1191, 1961.[Free Full Text]
• Doida, Y., and Okada, S.: Radiation-Induced Mitotic Delay in Cultured Mammalian Cells, Radiat Res 38:513-520, 1969.[CrossRef][Medline] [Order article via Infotrieve]
• Dixon, W.J., and Massey, F.J., Jr.: Introduction to Statistical Analysis, New York: McGraw-Hill, Inc., 1957.
• Wine, R.L.: Statistics for Scientists and Engineers, Prentice-Hall, Inc., Englewood Cliffs, NJ, 1964, p 209.
• Dewey, W.C., and Humphrey, R.M.: Relative Radio-sensitivity of Different Phases in the Life Cycle of L-P59 Mouse Fibroblasts and Ascites Tumor Cells, Radiat Res 16: 503-530, 1962.[CrossRef][Medline] [Order article via Infotrieve]
• Whitfield, J.F.; Brohee, H.; and Youdale, T.: The Effects of X Radiation on the Chromatin Structure and Histone Components of Rat Thymocyte Nuclei, Exp Cell Res 36:341-353, 1964.[CrossRef][Medline] [Order article via Infotrieve]
• Whitfield, J.F.; Brohee, H.; and Youdale, T.: Reduction of Mitotic Delay in Irradiated Suspension Cultures of Rat Thymocytes by an Elevated Salt Concentration, Exp Cell Res 35:207-210, 1964.[CrossRef][Medline] [Order article via Infotrieve]
• Whitfield, J.F., and Rixon, R.H.: Prevention of Post Irradiation Delay in Cultures of L Mouse Cells by Calcium Salts, Exp Cell Res 27:154-157, 1962.[CrossRef][Medline] [Order article via Infotrieve]
• Whitfield, J.F.; Rixon, R.H.; and Youdale, T.: Prevention of Mitotic Delay in Irradiated Suspension Cultures of L Mouse Cells by Agmatine, Exp Cell Res 27:143-195, 1962.[CrossRef][Medline] [Order article via Infotrieve]
• Hsu, T.C.; Dewey, W.C.; and Humphrey, R.M.: Radio-sensitivity of Cells of Chinese Hamsters In Vitro in Relation to the Cell Cycle, Exp Cell Res 27:441-452, 1962.[CrossRef][Medline] [Order article via Infotrieve]
• White, S.C.: Effects of Low-level X Radiation on Chromosomes, J Dent Res 46: (suppl), 1177-1181, 1967.[Free Full Text]
• Palmer, C.G. Et AL: The Action of Vincaleukoblastine on Mitosis In Vitro Exp Cell Res 20:198-201, 1960.
• Cutts, J.H.: The Effect of Vincaleukoblastine on Dividing Cells In Vivo, Cancer Research 21:168-172, 1961.[Abstract/Free Full Text]
• Malawista, S.E.; Sato, H. and Bensh, K.G.: Vinblastine and Griseofulvin Reversibly Disrupt the Living Mitotic Spindle, Science, 160:770-771, 1968.[Abstract/Free Full Text]

Journal of Dental Research, Vol. 48, No. 6, 1049-1053 (1969)
DOI: 10.1177/00220345690480060301


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Lurie, A. Search for Related Content PubMed PubMed Citation Articles by Lurie, A. Social Bookmarking                         What's this?