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The Origin of Collagenase in Periodontal Tissues of Man
Harold M. Fullmer
Department of Health, Education, and Welfare, National Institutes of Health, Bethesda, Maryland 20014
William A. Gibson
Department of Health, Education, and Welfare, National Institutes of Health, Bethesda, Maryland 20014
Gerald S. Lazarus
Department of Health, Education, and Welfare, National Institutes of Health, Bethesda, Maryland 20014
Howard A. Bladen
Department of Health, Education, and Welfare, National Institutes of Health, Bethesda, Maryland 20014
Karen A. Whedon
Department of Health, Education, and Welfare, National Institutes of Health, Bethesda, Maryland 20014
Collagenase is produced by both epithelial and connective tissue cells of the human gingiva. Collagenase action was shown through viscometry, acrylamide gel electrophoresis, and electron microscopy. Collagen is cleaved into one-quarter and three-quarter pieces by collagenase derived from human gingiva.
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Journal of Dental Research, Vol. 48, No. 5,
646-651 (1969)
DOI: 10.1177/00220345690480050701

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