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Journal of Dental Research
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Salivary Excretion of Lithium: II. Functional Analysis

Kenneth R. Spring

Veterans Administration Hospital, Leech Farm Road, Pittsburgh, Pennsylvania 15206

Morris A. Spirtes

Veterans Administration Hospital, Leech Farm Road, Pittsburgh, Pennsylvania 15206

Salivary Li+ was actively secreted by the cat submaxillary gland, inversely to the rate of flow, at concentrations above serum level. Stop-flow studies indicated ductal secretion of Li+ by a HgCl2 and ouabain-sensitive mechanism. Salivary secretion of Li+ did not resemble Na+ but was similiar to K+ secretion.

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Journal of Dental Research, Vol. 48, No. 4, 550-554 (1969)
DOI: 10.1177/00220345690480040901


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This Article
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