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Pharmacologic Control of Dentinal Fluid Movement and Dental Caries in Rats

School of Dentistry, Loma Linda University, Loma Linda, California

Parasympathetic stimulants were found to encourage the movement of fluid through the dentin from the pulp to the dentinoenamel junction. Regular treatment with a parasympathetic stimulant in rats that had all their major salivary glands removed significantly reduced the incidence of dental caries. Treatment with bradykinin in rats on a noncariogenic diet encouraged the movement of fluid into the tooth. When given regularly for 15 weeks, bradykinin caused significant dental caries.

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Journal of Dental Research, Vol. 47, No. 5, 720-724 (1968)
DOI: 10.1177/00220345680470051001


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Steinman, R. R. Search for Related Content PubMed PubMed Citation Articles by Steinman, R. R. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Social Bookmarking                         What's this?