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Figure 1. Identification of PTCH1 mutations in KC30. Nonsense mutation (c.403C>T) showed a homozygous pattern in DNA samples of KCOT, but was absent in peripheral blood DNA (left). Two concomitant polymorphisms (c.2913T>C; c.3141T>G) were homozygous in the tumor, but heterozygous in blood DNA (right), suggesting allelic loss (W, wild-type; T, KCOT tissue; B, peripheral blood).
J DENT RES, Vol. 87, No. 6,
575-579 (2008)
DOI: 10.1177/154405910808700616
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