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Figure 1. Immune cells in radicular granulomas. (A) A light micrograph of HLA-DR+ cells showing various profiles in radicular granuloma. Bar = 100 µm. (B) Higher magnification of the boxed area in (A). HLA-DR+ cells show dendritic (arrow) and spindle (arrowheads) profiles. These cells show cell-to-cell contacts with lymphocyte-like small round cells with a round nucleus. Bar = 50 µm. (C) A CD68+ cell showing an oval profile. This cell contains dense immunoreaction products in the cytoplasm. Bar = 30 µm. (D) A CD68+ cell showing a spindle profile with long cytoplasmic possesses. This cell contains sparse intracytoplasmic immunoreaction products. Bar = 30 µm. (E) Frequency of HLA-DR-, CD68-, CD3-, and CD28-positive cells in radicular granulomas. Results are expressed as mean ± SD (n=14 each). *p < 0.05 and **p < 0.01.
J DENT RES, Vol. 87, No. 6,
553-557 (2008)
DOI: 10.1177/154405910808700617
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