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Figure 1. Time-course of changes in the amount of tooth movement in wild-type mice and TNFR1/TNFR2-deficient mice. Histological images and numbers of TRAP-positive cells on the pressure side of the distobuccal root of the first molar during orthodontic tooth movement. (A) Changes in the amount of tooth movement in wild-type (closed square) and TNFR1/TNFR2-deficient (open circle) mice. Wild-type: n = 4 (2 days), 4 (4 days), 6 (6 days), 10 (10 days), 11 (12 days). TNFR1/TNFR2-deficient mice: n = 6 (2 days), 4 (4 days), 9 (6 days), 10 (10 days), 4 (12 days). (B) TRAP-stained transverse section of wild-type and TNFR1/TNFR2-deficient mice. (C) The number of TRAP-positive multinuclear cells in wild-type (black bar) and TNFR1/TNFR2-deficient (white bar) mice. Wild-type: n = 6. TNFR1/TNFR2-deficient mice: n = 4 each. *p < 0.05 by the Mann-Whitney U-test. Scale bar: 100 µm in (B). Results are expressed as means ± SD.
J DENT RES, Vol. 87, No. 4,
396-400 (2008)
DOI: 10.1177/154405910808700405
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