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Journal of Dental Research
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Figure 4


Figure 4. AN-0128 reduces alveolar bone loss. We induced periodontitis by placing ligatures around the right and left second molars for 7 days. Molar teeth were treated with 5% AN-0128 (5% AN), vehicle alone (V), or Total toothpaste (T) on a daily basis. One control group had no ligatures (NL), and another had ligatures placed but no treatment (Lig). Bone volume (A) or bone loss (B) was assessed by micro-CT. Results represent the mean of 6 animals ± SEM. *Significantly different compared with ’ligature only’ (P < 0.05).

J DENT RES, Vol. 87, No. 2, 148-152 (2008)
DOI: 10.1177/154405910808700208





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