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Figure 3. Both LRAP and P172 induce the proliferation of cementoblast/periodontal ligament cells. (A) Amelogenin-KO (KO) cementoblast/periodontal ligament cells showed reduced proliferation. **P < 0.01. (B,C) Increased proliferation rate of KO cementoblast/periodontal ligament cells treated with either LRAP or P172. Amelogenin-KO cementoblast/periodontal ligament cells were cultured with various concentrations of LRAP (B) or P172 (C) for 1, 3, and 5 days. *P < 0.05 vs. day 0, **P < 0.01 vs. day 0, #P < 0.05 vs. 0 ng/mL group, and ##P < 0.01 vs. 0 ng/mL group. (D,E) Wild-type (WT) cementoblast/periodontal ligament cells were cultured with various concentrations of LRAP (D) or P172 (E) for 1, 3, or 5 days. Data are expressed as the mean ± SD (n = 3). *P < 0.05 vs. day 0, **P < 0.01 vs. day 0, #P < 0.05 vs. 0 ng/mL group, and ## P < 0.01 vs. 0 ng/mL group.
J DENT RES, Vol. 85, No. 2,
144-149 (2006)
DOI: 10.1177/154405910608500206
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