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Figure 1. Cartoon of perlecan domain structure with 3 glycosaminoglycan chains, typically heparan sulfate, covalently attached to domain I of the protein core. Various homologies and purported functions are ascribed to each domain. SMC, smooth-muscle cell; EC, endothelial cell; FGF, fibroblast growth factor; MMP, matrix metalloproteinase; EGF, epithelial growth factor; LDL, low-density lipoprotein; ECM, extracellular matrix.
J DENT RES, Vol. 85, No. 2,
122-132 (2006)
DOI: 10.1177/154405910608500203
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