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Figure 1. Transcriptional activity of CD14/-159C and CD14/-159T. CD14/-159T has enhanced transcriptional activity in reporter assays. THP-1 cells were transiently transfected with -159C/luc, -159T/luc, or pGL3-Basic (1 µg). Luciferase activity was normalized for transfection efficiency with the use of a control plasmid pRL-TK (25 ng) and protein concentration. Results are fold increase in relative luciferase activity (RLA) of the CD14 reporter constructs compared with the empty control vector pGL3-Basic. The data are presented as mean ± SEM of 3 replicates. *Significant at p = 0.015 (unpaired t test).
J DENT RES, Vol. 82, No. 8,
612-616 (2003)
DOI: 10.1177/154405910308200808
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