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Figure 2. S. mutans LTA induced VEGF expression in MDPC-23 (A) and OD-21 (B). VEGF concentration was determined by ELISA from the conditioned medium of cells treated with 0-80 µg/mL S. mutans LTA for 24 hrs. We performed Trypan blue assays to normalize the VEGF concentration by the number of viable cells per well. Control was recombinant mouse VEGF. Each graph depicts the mean values + SEM of triplicate wells per cell type and LTA concentration, and is representative of three independent experiments. Asterisk indicates statistical significance at p < 0.05.
J DENT RES, Vol. 82, No. 6,
466-470 (2003)
DOI: 10.1177/154405910308200612
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