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Figure 3. Distribution patterns of p-JNK, p-c-Jun, and HSPs 4 and 14 days after injury. (a-h) Four days after injury. Signals of p-JNK (black arrowheads in a) and p-c-Jun (white arrowheads in c) were detected only in nuclei of some pulp cells close to odontoblasts, not in pulp cells far from odontoblasts (b,d). HSP70 (black arrows in f) relocalized from the nucleus to the cytoplasm of pulp cells. HSP27 (white arrows in h) was strongly detected in the cytoplasm of pulp cells. There were no changes in distribution patterns of HSPs in odontoblasts (e,g). (j-q) Fourteen days after injury. Both signals of p-JNK (black arrowheads in j) and p-c-Jun (white arrowheads in l) were observed in pulp cells close to odontoblasts, not in other pulp cells (k,m). Levels of HSP70 (black arrows in n,o) and HSP27 (white arrows in p,q) in odontoblasts and pulp cells returned to those in non-treated molars. OBR, odontoblast region; PC, pulp cells; ob, odontoblasts. Scale bar = 10 µm.
J DENT RES, Vol. 82, No. 2,
91-95 (2003)
DOI: 10.1177/154405910308200203
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