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Journal of Dental Research
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Tumor Necrosis Factor-{alpha}-converting Enzyme (TACE) Levels in Periodontal Diseases

N. Bostanci1, G. Emingil2, B. Afacan2, B. Han2, T. Ilgenli2, G. Atilla2, F.J. Hughes1 and G.N. Belibasakis1,*

1 Centre for Adult Oral Health, Bart’s and the London School of Medicine and Dentistry, Queen Mary University of London, Turner Street, E1 2AD London, UK; and
2 Department of Periodontology, School of Dentistry, Ege University, Izmir, Turkey


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  		Figure 1. Distribution of total TACE amounts in GCF from healthy persons (n = 21), those with gingivitis (n = 22), chronic periodontitis (n = 28), aggressive periodontitis (n = 25), and immunosuppressed persons with chronic (IS-Chronic) periodontitis (n = 11). The individual values represent the total amounts of TACE (pg/30 sec) in each person. Values significantly different from those in healthy persons (*p < 0.001) and those with gingivitis (+p < 0.005).

 

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  		Figure 2. Distribution of TACE concentrations in GCF from healthy persons (n = 21), those with gingivitis (n = 22), chronic periodontitis (n = 28), aggressive periodontitis (n = 25). and immunosuppressed persons with chronic (IS-Chronic) periodontitis (n = 11). The individual values represent the concentrations of TACE (pg/µL) in each person. Values significantly different from those in persons with gingivitis (*p < 0.001) and immunosuppressed persons with chronic periodontitis (+p < 0.005).

 

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  		Figure 3. Scatter plot showing the correlation between TACE and RANKL concentrations (pg/µL) in GCF. A positive correlation was revealed (r = 0.243, p = 0.006). These GCF RANKL concentration data have previously been reported (Bostanci et al., 2007a).

 

Journal of Dental Research, Vol. 87, No. 3, 273-277 (2008)
DOI: 10.1177/154405910808700311
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