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Journal of Dental Research
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Antimicrobial Effect of Nanometric Bioactive Glass 45S5

T. Waltimo1, T.J. Brunner2, M. Vollenweider2, W.J. Stark2 and M. Zehnder3,*

1 Institute of Oral Microbiology and Preventive Dentistry, University of Basel Center of Dental Medicine, Switzerland;
2 Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland; and
3 Department of Preventive Dentistry, Periodontology, and Cariology, University of Zürich Center of Dental Medicine, Plattenstrasse 11, CH-8032 Zürich, Switzerland


Figure 1
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  		Figure 1. Scanning electron microscopic images of flame-derived, nanometric bioactive glass (left) and the micron-sized commercially available 45S5 glass used in this study (PerioglassTM, right).

 

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  		Figure 2. Silicon and calcium contents as well as pH levels of 1:10 (wt/vol) suspension supernatants of conventional and nanoparticulate bioglass in simulated body fluid. Error bars indicate standard deviations (N = 3).

 

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  		Figure 3. Recovered viable E. faecalis ATCC 29212 cells after direct exposure to test and control materials in simulated body fluid over time. Mean log10 CFU values (N = 3); error bars = standard deviations.

 

Journal of Dental Research, Vol. 86, No. 8, 754-757 (2007)
DOI: 10.1177/154405910708600813
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