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Journal of Dental Research
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Photodynamic Therapy in Dentistry

K. Konopka1,* and T. Goslinski2

1 Department of Microbiology, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, CA, USA; and
2 Department of Chemical Technology of Drugs, University of Medical Sciences, Poznan, Poland


Figure 1
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  		Figure 1. Schematic representation of photodynamic reaction and photodynamic therapy. Light (photon) of an appropriate energy (e.g., with wavelength at the absorption maximum) is absorbed by a photosensitizer, which undergoes a transition from a low-energy ground state to the excited-singlet state. The activated photosensitizer interacts with oxygen to produce singlet oxygen and other radical species that cause a toxic effect in tumor cells or micro-organisms; ROS, reactive oxygen species.

 

Figure 2
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  		Figure 2. Photosensitizers used in photodynamic therapy.

 

Figure 3
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  		Figure 3. Photosensitizers used in the different clinical applications of photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT).

 

Journal of Dental Research, Vol. 86, No. 8, 694-707 (2007)
DOI: 10.1177/154405910708600803
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