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Journal of Dental Research
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Strong Genetic Control of Emergence of Human Primary Incisors

T.E. Hughes1,*, M.R. Bockmann1, K. Seow2, T. Gotjamanos3, N. Gully1, L.C. Richards1 and G.C. Townsend1

1 School of Dentistry, The University of Adelaide, Frome Rd., Adelaide, Australia 5005;
2 School of Dentistry, The University of Queensland, Australia; and
3 School of Medicine, The University of Notre Dame, Australia


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  		Figure. Path diagrams illustrating additive genetic (A) and non-shared environmental (E) factor loadings on the timing of primary incisor emergence. Each diagram represents one member of a same-sex twin pair. Squares represent observed variables; circles represent latent variables. Single-headed arrows define causal relationships between and among variables; double-headed arrows represent covariance. Sexual heterogeneity was observed for several small, but statistically significant, genetic loadings upon antimeric pairs and lateral incisors, and hence diagrams are presented for both males and females. However, most observed phenotypic variation was explained in both males and females by a general genetic factor loading on all 8 teeth.

 

Journal of Dental Research, Vol. 86, No. 12, 1160-1165 (2007)
DOI: 10.1177/154405910708601204
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