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Journal of Dental Research
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Angiogenesis Inhibitors and the Need for Anti-angiogenic Therapeutics

C.R. Dass1,*, T.M.N. Tran1 and P.F.M. Choong1,2

1 Department of Orthopaedics, University of Melbourne, St. Vincent’s Health, P.O. Box 2900, Fitzroy, 3065, Melbourne, Australia; and
2 Bone and Soft Tissue Sarcoma Service, Peter MacCallum Cancer Centre, Melbourne, Australia


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Figure. Basic feedback loop between a tumor and its suppliant vasculature. Most critical is the delicate balance between pro- and anti-angiogenic signals in the tumor and surrounding milieu.

 

Journal of Dental Research, Vol. 86, No. 10, 927-936 (2007)
DOI: 10.1177/154405910708601005


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