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Journal of Dental Research
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Preventive Intervention Possibilities in Radiotherapy- and Chemotherapy-induced Oral Mucositis: Results of Meta-analyses

M.A. Stokman1,*, F.K.L. Spijkervet1, H.M. Boezen2, J.P. Schouten2, J.L.N. Roodenburg1 and E.G.E. de Vries3

1 Departments of Oral and Maxillofacial Surgery,
2 Epidemiology and Statistics, and
3 Medical Oncology, University of Groningen and University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands


Figure 1
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  		Figure 1. The development of mucositis in a 5-stage model (adapted from Sonis [2004]) and possible pathways of intervention for mucositis prevention.

 

Figure 2
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  		Figure 2. Standard meta-analysis plot results of PTA for the outcome "presence of ulceration".

 

Figure 3
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  		Figure 3. Standard meta-analysis plot results of GM-CSF/G-CSF (systemic administration) for the outcome "presence of mucositis".

 

Figure 4
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  		Figure 4. Standard meta-analysis plot results of oral cooling for the outcome "presence of mucositis".

 

Figure 5
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  		Figure 5. Standard meta-analysis plot results of amifostine for the outcome "presence of grade 3 and grade 4 mucositis".

 

Journal of Dental Research, Vol. 85, No. 8, 690-700 (2006)
DOI: 10.1177/154405910608500802
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