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Journal of Dental Research
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Clinical

In situ Mineral Loss Inhibition by CO2 Laser and Fluoride

L.K.A. Rodrigues1, M. Nobre dos Santos2,* and J.D.B. Featherstone3

1 Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, CE, Brazil;
2 Faculty of Dentistry of Piracicaba, State University of Campinas, Av. Limeira 901, Piracicaba, SP, 13414-903, Brazil; and
3 University of California, San Francisco, CA, USA

Correspondence: * corresponding author, nobre{at}fop.unicamp.br

Laser and fluoride treatments have been shown to inhibit enamel demineralization in the laboratory. However, the intra-oral effects of this association have not been tested. This study assessed in situ the effect of a Transversely Excited Atmospheric CO2 laser ({lambda} = 9.6 µm) and the use of pressure fluoridated dentifrice on enamel demineralization. During two 14-day phases, 17 volunteers wore palatal appliances containing human enamel slabs assigned to treatment groups, as follows: (1) non-fluoride dentifrice, (2) CO2 laser irradiation plus non-fluoride dentifrice, (3) fluoride dentifrice, and (4) CO2 laser irradiation plus fluoride dentifrice. A 20% sucrose solution was dripped onto the slabs 8 times per day. The specimens treated with laser and/or fluoridated dentifrice presented a significantly lower mineral loss when compared with those from the non-fluoride dentifrice group. The results suggested that CO2 laser treatment of enamel inhibits demineralization in the human mouth, being more effective when associated with fluoride.

Key Words: CO2 laser • fluoride • dental enamel • demineralization • dental caries

Journal of Dental Research, Vol. 85, No. 7, 617-621 (2006)
DOI: 10.1177/154405910608500707
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