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Journal of Dental Research
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Biomaterials & Bioengineering

Polyelectrolyte Multilayer Film Coating and Stability at the Surfaces of Oral Prosthesis Base Polymers: an in vitro and in vivo Study

O. Etienne1,2, C. Picart1, C. Taddei2, P. Keller1, E. Hubsch3, P. Schaaf3, J.C. Voegel1, Y. Haikel2, J.A. Ogier1 and C. Egles1,*

1 Institut National de la Santé et de la Recherche Médicale, Unité 595, 11, rue Humann, 67085 Strasbourg Cedex, France;
2 Faculté de Chirurgie Dentaire, Université Louis Pasteur, 1, Place de l’hôpital, 67000 Strasbourg, France; and
3 Institut Charles Sadron, UPR 22 CNRS, 6 rue Boussingault, 67083 Strasbourg Cedex, France

Correspondence: * corresponding author, new address, Division of Cancer Biology and Tissue Engineering, Tufts University, School of Dental Medicine, 55 Kneeland Street, Boston, MA 02111, USA; christophe.egles{at}tufts.edu

A new type of coating involving a layer-by-layer technique has been recently reported. This coating is composed of a polyelectrolyte multilayer film that confers specific properties on surfaces to which it is applied. Here, we studied the applicability of such a technique to the coating of oral prostheses, by first testing the construction of polyelectrolyte multilayer films on several polymers used in oral prosthesis bases, and, subsequently, by studying the stability of these coatings in vitro, in human saliva, and in vivo in a rat model. We demonstrated that the multilayered films are able to coat the surfaces of all tested polymers completely, thus increasing their wettability. We also showed that saliva does not degrade the film after 7 days in vitro and after 4 days in vivo. Taken together, our results establish that the layer-by-layer technique is suitable for the coating of oral devices.

Key Words: surface treatment • polyelectrolyte multilayer film • denture base polymer • coating

Journal of Dental Research, Vol. 85, No. 1, 44-48 (2006)
DOI: 10.1177/154405910608500107
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