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Journal of Dental Research
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Clinical

Efficacy of Silver Diamine Fluoride for Caries Reduction in Primary Teeth and First Permanent Molars of Schoolchildren: 36-month Clinical Trial

J.C. Llodra1,*, A. Rodriguez2, B. Ferrer2, V. Menardia3, T. Ramos2 and M. Morato3

1 Department of Preventive Dentistry, School of Dentistry, University of Granada, Granada 18071, Spain;
2 School of Dentistry, Institute of Medical Science, University of Santiago de Cuba, Cuba; and
3 Odontologia Solidaria NGO, Spain;

Correspondence: * corresponding author, jllodra{at}hotmail.com.

We hypothesized that the six-monthly application of silver diamine fluoride (SDF) can arrest the development of caries in the deciduous dentition of six-year-old schoolchildren and prevent caries in their first permanent molars. A prospective controlled clinical trial was conducted on the efficacy of a 38% SDF solution for caries reduction. Four hundred and twenty-five six-year-old children were divided into two groups: One group received SDF solution in primary canines and molars and first permanent molars every 6 mos for 36 mos. The second group served as controls. The 36-month follow-up was completed by 373 children. The mean number of new decayed surfaces appearing in primary teeth during the study was 0.29 in the SDF group vs. 1.43 in controls. The mean of new decayed surfaces in first permanent molars was 0.37 in the SDF group vs. 1.06 in controls. The SDF solution was found to be effective for caries reduction in primary teeth and first permanent molars in schoolchildren.

Key Words: clinical trial • dental caries • preventive dentistry • silver diamine fluoride

Journal of Dental Research, Vol. 84, No. 8, 721-724 (2005)
DOI: 10.1177/154405910508400807
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R. Yee, C. Holmgren, J. Mulder, D. Lama, D. Walker, and W. van Palenstein Helderman
Efficacy of Silver Diamine Fluoride for Arresting Caries Treatment
Journal of Dental Research, July 1, 2009; 88(7): 644 - 647.
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A. Rosenblatt, T.C.M. Stamford, and R. Niederman
Silver Diamine Fluoride: A Caries "Silver-Fluoride Bullet"
Journal of Dental Research, February 1, 2009; 88(2): 116 - 125.
[Abstract] [Full Text] [PDF]