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Journal of Dental Research
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CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE

Hereditary Blood Coagulation Disorders: Management and Dental Treatment

G. Gómez-Moreno1, A. Cutando-Soriano1,*, C. Arana2 and C. Scully3

1 Department of Special Care in Dentistry, School of Dentistry, University of Granada, Colegio Máximo s/n, Campus de Cartuja, E-18071 Granada, Spain;
2 Department of Physiology, Institute of Biotechnology, University of Granada, Granada, Spain; and
3 Eastman Dental Institute, University College, London, UK;

Correspondence: * corresponding author, acutando{at}ugr.es

Patients with hereditary hemostatic disorders, characterized by a tendency to bleeding or thrombosis, constitute a serious challenge in the dental practice. Advances in the medical diagnosis of hemostatic disorders have exposed dental professionals to new patients not amenable to the application of the management protocols associated with other, more well-known, disorders. It is the aim of this paper to review the evidence, to highlight the areas of major concern, and to suggest management regimens for patients with hereditary hemostatic disorders. An extensive review has been made (PubMed, Science Direct, Web of Knowledge, etc.) of literature pertaining to hereditary disorders affecting blood coagulation factors and how they affect the practice of dentistry. Several aspects relating to the care of such patients must be recognized and taken into consideration when dental treatment is planned. Replacement of deficient coagulation factors ensures that safe dental treatment will be carried out. However, the half-life of such coagulation factors requires that dental treatment be specifically planned and adapted to the type of pathology involved.

Key Words: hereditary coagulation disorders • dental treatment

Journal of Dental Research, Vol. 84, No. 11, 978-985 (2005)
DOI: 10.1177/154405910508401102
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