Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Korszun, A.
Right arrow Articles by Crofford, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Korszun, A.
Right arrow Articles by Crofford, L.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Clinical

Basal Circadian Cortisol Secretion in Women with Temporomandibular Disorders

A. Korszun1,*, E.A. Young2, K. Singer2, N.E. Carlson3, M.B. Brown3 and L. Crofford4

1 Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK;
2 Department of Psychiatry, University of Michigan, Ann Arbor, USA;
3 Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, USA; and
4 Department of Internal Medicine, University of Michigan, Ann Arbor, USA;

Correspondence: *corresponding author, akorszun{at}umich.edu

Muscular temporomandibular disorder (TMD) is a common stress-related condition showing marked comorbidity with depression and fibromyalgia (FM), both of which are associated with dysregulation of cortisol secretion. We measured cortisol levels in 15 women with well-defined TMD and 15 matched controls by sampling blood at 10-minute intervals over 24 hours in a controlled environment. TMD patients showed markedly increased daytime cortisol levels 30% to 50% higher than those of controls (p = 0.0032) and a one-hour phase delay in the timing of maximum cortisol levels (p = 0.048). Increased activation of the stress hormone axis by conscious pain perception is a likely explanation, but the magnitude of the increase could indicate that pain in the facial region acts as a greater stimulus than pain elsewhere in the body.

Key Words: cortisol • temporomandibular disorders • facial pain

Journal of Dental Research, Vol. 81, No. 4, 279-283 (2002)
DOI: 10.1177/154405910208100411
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Psychosom. Med.Home page
J. J. Sherman, L. LeResche, K. H. Huggins, L. A. Mancl, J. C. Sage, and S. F. Dworkin
The Relationship of Somatization and Depression to Experimental Pain Response in Women With Temporomandibular Disorders
Psychosom Med, November 1, 2004; 66(6): 852 - 860.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. Okamoto, H. Hirata, S. Takeshita, and D. A. Bereiter
Response Properties of TMJ Units in Superficial Laminae at the Spinomedullary Junction of Female Rats Vary Over the Estrous Cycle
J Neurophysiol, March 1, 2003; 89(3): 1467 - 1477.
[Abstract] [Full Text] [PDF]